The promises and challenges of toxico-epigenomics: environmental chemicals and their impacts on the epigenome
… as epigenetic disruptors. We also discuss the advantages and challenges of using epigenetic
… risk assessment, and our perspectives on the future role of epigenetics in toxicology. …
… risk assessment, and our perspectives on the future role of epigenetics in toxicology. …
Epigenetic alterations caused by aflatoxin b1: a public health risk in the induction of hepatocellular carcinoma
RG Ferreira, MV Cardoso, KM De Souza Furtado… - Translational …, 2019 - Elsevier
… studied mycotoxin due to its great toxicity, its distribution in a … HCC through genetic and
epigenetic modifications. The genetic … for AFB1-induced epigenetic alterations and the potential …
epigenetic modifications. The genetic … for AFB1-induced epigenetic alterations and the potential …
Epigenetic reprogramming and potential application of epigenetic-modifying drugs in acquired chemotherapeutic resistance
L Ponnusamy, PKS Mahalingaiah, KP Singh - Advances in clinical …, 2020 - Elsevier
… The fluid and reversible nature of epigenetic signaling not … as chemotherapy-induced toxicity
and contributing for increased cell … , autophagy signal involves different signaling pathways …
and contributing for increased cell … , autophagy signal involves different signaling pathways …
[HTML][HTML] Untoward effects of micro-and nanoplastics: an expert review of their biological impact and epigenetic effects
… signaling pathways, modify the gut microbiota composition, and may induce important epigenetic
… increasing resistance to NP toxicity and by regulating several epigenetic-related genes …
… increasing resistance to NP toxicity and by regulating several epigenetic-related genes …
An overview of epigenetic agents and natural nutrition products targeting DNA methyltransferase, histone deacetylases and microRNAs
… nutrition were discovered to alter the epigenetic states of cells. The … This review mainly
summarizes the information of epigenetic … related to the epigenetic therapy are also included. …
summarizes the information of epigenetic … related to the epigenetic therapy are also included. …
[HTML][HTML] Metabolic and epigenetic reprogramming in the arsenic-induced cancer stem cells
… factors, the metabolic and epigenetic reprogramming, during the … and epigenetic signaling
pathways for cancer therapy. … are the most likely target of As 3+ toxicity [24,25]. Unequivocal …
pathways for cancer therapy. … are the most likely target of As 3+ toxicity [24,25]. Unequivocal …
[HTML][HTML] The anti-cancer drug doxorubicin induces substantial epigenetic changes in cultured cardiomyocytes
… and necrosis in healthy tissue causing toxicity in the brain, liver, … stress implied in DOX toxicity
may exert direct effects on … -mediated dysregulation of epigenetic signaling proteins nicely …
may exert direct effects on … -mediated dysregulation of epigenetic signaling proteins nicely …
[HTML][HTML] A chemical biology toolbox to study protein methyltransferases and epigenetic signaling
… for the study of methylation-mediated signaling in epigenetics, inflammation and beyond. …
range of epigenetic and non-epigenetic methylation-mediated signaling pathways and biology. …
range of epigenetic and non-epigenetic methylation-mediated signaling pathways and biology. …
Chemical activation of estrogen and aryl hydrocarbon receptor signaling pathways and their interaction in toxicology and metabolism
P Tarnow, T Tralau, A Luch - … on drug metabolism & toxicology, 2019 - Taylor & Francis
… signaling cascades and molecular crosstalk remain sparsely understood. Amongst other
reasons, this is often caused by a toxicological focus … and toxicological roles of both signaling …
reasons, this is often caused by a toxicological focus … and toxicological roles of both signaling …
[HTML][HTML] ROS promote epigenetic remodeling and cardiac dysfunction in offspring following maternal engineered nanomaterial (ENM) exposure
A Kunovac, QA Hathaway, MV Pinti… - … and Fibre Toxicology, 2019 - Springer
… to epigenetic alterations [11, 13]. DNA methylation of cytosine, forming 5-methylcytosine (5mC),
was one of the first epigenetic … epigenetic memory by propagating the initial signal, …
was one of the first epigenetic … epigenetic memory by propagating the initial signal, …