[HTML][HTML] Burkitt lymphomas evolve to escape dependencies on Epstein-Barr virus

RL Hutcheson, A Chakravorty… - Frontiers in cellular and …, 2021 - frontiersin.org
… , it will be important to attribute mechanisms to the identified mutations so we might further
understand these EBV-associated cancers and their evolution to treat them more effectively. …

Prophylactic and therapeutic strategies for EpsteinBarr virus-associated diseases: emerging strategies for clinical development

V Dasari, D Sinha, MA Neller, C Smith… - Expert review of …, 2019 - Taylor & Francis
Introduction: EpsteinBarr virus (EBV) infects more than 95% of the world’s population and
is associated with infectious mononucleosis as well as a number of cancers in various …

[HTML][HTML] Epstein Barr virus: development of vaccines and immune cell therapy for EBV-associated diseases

X Cui, CM Snapper - Frontiers in Immunology, 2021 - frontiersin.org
treatment of cancers. Adoptive T-cell therapy has been successfully used in the prevention
and treatment … EBV reactivation, termed PTLD that can evolve into Hodgkin lymphoma or non-…

Epstein-Barr virus (EBV) reactivation and therapeutic inhibitors

JR Kerr - Journal of clinical pathology, 2019 - jcp.bmj.com
… , including drugs licensed for treatment of other herpesviruses, … EBV proteins, Epstein-Barr
nuclear antigens EBNA3, EBNA4 … But how they arise and evolve during primary EBV infection …

[HTML][HTML] EpsteinBarr virus in multiple sclerosis: theory and emerging immunotherapies

A Bar-Or, MP Pender, R Khanna, L Steinman… - Trends in molecular …, 2020 - cell.com
… demonstrating a link between B cell-tropic EpsteinBarr virus (EBV) and disease onset.
Efforts to develop antiviral strategies for treating MS are underway. Although gaps remain in our …

[HTML][HTML] Advances in the study of chronic active Epstein-Barr virus infection: clinical features under the 2016 WHO classification and mechanisms of development

A Arai - Frontiers in pediatrics, 2019 - frontiersin.org
… to start treatment before these conditions develop. At present, the only effective treatment
reported that CAEBV patients showed clonal evolution of the infected cells and eventually …

[HTML][HTML] Epsteinbarr virus history and pathogenesis

H Yu, ES Robertson - Viruses, 2023 - mdpi.com
… for recognizing and identifying early and effective treatments at different stages in the …
The fact that EBV persists for the lifetime of the host indicates that it has evolved successful …

[HTML][HTML] Novel therapies boosting T cell immunity in epstein barr virus-associated nasopharyngeal carcinoma

S Renaud, A Lefebvre, S Mordon, O Moralès… - International Journal of …, 2020 - mdpi.com
treatments. Multiple aetiological factors have been described including environmental factors,
genetics, and viral factors (Epstein Barr Virus, EBV), making NPC treatment that … evolution

EpsteinBarr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV

C Venturini, CJ Houldcroft, A Lazareva… - British Journal of …, 2021 - Wiley Online Library
treatment. These findings are compatible with CAEBV being associated with the evolution
and persistence of EBV + haematological clones that are lost on successful treatment. …

[HTML][HTML] Evolution of functional antibodies following acute Epstein-Barr virus infection

CB Karsten, YC Bartsch, SA Shin, MD Slein… - PLoS …, 2022 - journals.plos.org
While Epstein-Barr virus causes mostly asymptomatic infection, associated malignancies,
and autoimmune and lymphoproliferative diseases occur. To dissect the evolution of humoral …