Estrogen-related receptor alpha induces epithelial-mesenchymal transition through cancer-stromal interactions in endometrial cancer

K Yoriki, T Mori, T Kokabu, H Matsushima… - Scientific reports, 2019 - nature.com
Estrogen-related receptor alpha (ERRα), which shares structural similarities with estrogen
receptors, is associated with tumor progression in endometrial cancer, but little is known about …

The role of ERα36 in cell type-specific functions of estrogen and cancer development

F Mahboobifard, L Dargahi, M Jorjani… - Pharmacological …, 2021 - Elsevier
… It is also suggested to be an important estrogen receptor involved in preserving bone in …
found between estrogen receptors and CD31 [65]. Finally, in triple-negative breast carcinoma, …

G protein-coupled estrogen receptor in cancer and stromal cells: functions and novel therapeutic perspectives

RA Pepermans, G Sharma, ER Prossnitz - Cells, 2021 - mdpi.com
… Its role in driving estrogen receptor-expressing breast … One of its receptors, the G
protein-coupled estrogen receptor … value of targeting this estrogen receptor as a potential …

Targeting inhibition of prognosis-related lipid metabolism genes including CYP19A1 enhances immunotherapeutic response in colon cancer

L Liu, M Mo, X Chen, D Chao, Y Zhang, X Chen… - Journal of Experimental …, 2023 - Springer
… Human colon carcinoma tissue microarray (HCol-Ade180Sur-05) containing … estrogen
receptor 30 (GPR30) promotes colon cancer growth through mediating estrogenic activity in colon

G protein-coupled estrogen receptor, GPER1, offers a novel target for the treatment of digestive diseases

C DeLeon, DQH Wang, CK Arnatt - Frontiers in Endocrinology, 2020 - frontiersin.org
… However, the roles of estrogen in the regulation of … of the G protein-coupled estrogen receptor
(GPER1). Although many … signaling pathways of three estrogen receptors, highlights the …

ESRRA (estrogen related receptor alpha) is a critical regulator of intestinal homeostasis through activation of autophagic flux via gut microbiota

S Kim, JY Lee, SG Shin, JK Kim, P Silwal, YJ Kim… - Autophagy, 2021 - Taylor & Francis
… The ESRR (estrogen related receptor) family consists of three subfamilies, including the first
identified orphan nuclear receptor ESRRA/NR3B1 (estrogen related receptor alpha), ESRRB…

Antiproliferative and cytotoxic activity of xanthohumol and its non-estrogenic derivatives in colon and hepatocellular carcinoma cell lines

IE Logan, CL Miranda, MB Lowry, CS Maier… - International journal of …, 2019 - mdpi.com
colon carcinoma cell line Caco-2, breast carcinoma line MCF-7, the melanoma line SK-MEL-28,
and a Burkitt lymphoma cell line [21,22,23,24,25]. The estrogenic … for estrogen receptors

Activity of estrogen receptor β agonists in therapy-resistant estrogen receptor-positive breast cancer

J Datta, N Willingham, JM Manouchehri… - Frontiers in …, 2022 - frontiersin.org
… However, there has been limited study of the role of ERβ in estrogen receptor α-positive
breast cancer. One reason is that for this particular indication a high degree of selectivity for ERβ …

The sex-related interplay between tme and cancer: On the critical role of estrogen, micrornas and autophagy

P Matarrese, G Mattia, MT Pagano, G Pontecorvi… - Cancers, 2021 - mdpi.com
… have been identified so far: the estrogen receptor alpha (ERα) [48,49], and the estrogen
and hepatocellular carcinoma, and it suppresses anti-estrogenic treatment resistance in human …

Reprogramming of mesothelial-mesenchymal transition in chronic peritoneal diseases by estrogen receptor modulation and TGF-β1 inhibition

RB Wilson, R Archid, MA Reymond - International Journal of Molecular …, 2020 - mdpi.com
Estrogen receptors act at the cell membrane/cytosol as … way to other receptor tyrosine
kinases; or can activate the estrogen … cells and intraperitoneal Lewis lung carcinoma. Combining …