… important predictor of hepatic inflammation and fibrosis [73], … tissue and the liver, and the
liver occupies a central role in relevant metabolic pathophysiology such as NAFLD and fibrosis …

… On a pathophysiological level, fibrotic remodelling of the myocardium could disrupt appropriate
myocardial excitation–contraction coupling and may promote arrhythmia, eg through the …

… design of therapies aimed at precisely modulating inflammation, fibrosis and tissue repair
28 . … 44 , highlighting the diverse pathophysiological roles of these cells in different organs. …

… Tissue fibrosis, the excessive or dysregulated deposition of extracellular matrix (ECM) …
common pathophysiologic companion of a wide range of diseases. Although significant fibrosis is …

… Cardiac fibrosis is a common pathophysiologic … fibrosis, a process that is critical for
preservation of the structural integrity of the infarcted ventricle. On the other hand, pathophysiologic …

… impact of moMacs on the pathophysiology of the disease. … and inflammation in adipose
tissue associate with fibrosis … adipose tissue section obtained from (a) lean (without fibrosis…

… fibrotic tissue that leads to hepatic fibrosis. Reactive oxygen species (ROS) can directly activate
HSCs or induce inflammation … to produce large amounts of fibrotic proteins. Furthermore, …

… 3 days before injury, the inflammatory damage and fibrosis levied by UUO is markedly
reduced. PAS, … role in the pathophysiology of kidney fibrosis. Indeed, novel therapies for renal …

… important pathophysiological features in the … Inflammation results in edema and is a common
feature of both acute ischemic and nonischemic myocardial injury. The pathophysiological …

… , and remodeling, all of which contribute to tissue remodeling and fibrosis, are altered.
Many cytokines and pathophysiological circumstances can cause the production of CTGF. Its …