… of fibrogenesis in the liver and onset of hepatic fibrosis. It starts off as a process meant to …
liver fibrosis. There are many inflammation-related pathways activated during liver fibrosis that …

… , the cell types involved in SSc pathophysiology also show evidence of an endogenous
oxidative stress. Fibroblasts extracted from either fibrotic or non fibrotic skin of patients with SSc …

… common, underlying pathophysiological mechanisms of fibrosis involving pathways associated
… and mediated by varying degrees of inflammation and fibrosis.5 ILDs may arise from a …

… marrow fibrosis … inflammatory hypothesis of MPN pathophysiology, a hypothesis that has
been applied to other cancers as well: namely, that inflammation, particularly via inflammatory …

… ) that attract inflammatory cells and in a chronic setting create the milieu for the development
of fibrosis around the portal space. This periportal fibrosis eventually would progress into …

… inflammation and regeneration that cannot be resolved, and normal tissue is replaced with
non-functional scar tissue… the key principles of inflammation and fibrosis, emphasizing current …

… the intestine in both physiology and pathophysiology. Over the last … inflammation, for instance,
due to lack of response to therapy, may drive deranged repair responses leading to fibrotic …

… is upregulated in fibrotic liver tissue and promotes pro-inflammatory cytokine expression, …
Consideration of the complex disease pathophysiology, implementation of complementary …

… Moreover, inflammatory cytokines and signaling regulators activated upon exposure to
infection or various stresses play crucial roles in the pathological function of parenchymal cells, …

… There is a growing evidence suggesting that inflammation … to IPAH, whereas intimal fibrosis
was generally rare and mild. … , more inflammatory cells were found in RV tissue samples of …