[HTML][HTML] Pathophysiology of Crohn's disease inflammation and recurrence

L Petagna, A Antonelli, C Ganini, V Bellato… - Biology direct, 2020 - Springer
inflammation plays a key role. Crohn’s disease evolution is mediated by a complex alteration
of the inflammatory … This review will highlight the role of inflammation in CD and describe …

[HTML][HTML] Inflammation and fibrosis in chronic liver diseases including non-alcoholic fatty liver disease and hepatitis C

S Tanwar, F Rhodes, A Srivastava… - World journal of …, 2020 - ncbi.nlm.nih.gov
… by which liver inflammation and fibrosis develop in chronic liver … Finally, the evidence for
hepatic fibrosis regression and the … in furthering our understanding of hepatic pathophysiology. …

[HTML][HTML] Systemic sclerosis: from pathophysiology to novel therapeutic approaches

D Benfaremo, S Svegliati, C Paolini, S Agarbati… - Biomedicines, 2022 - mdpi.com
… Interleukin (IL)-33 is an alarmin of the IL-1 family related to inflammation and fibrosis and …
and CD163) in microarrays of lung tissue from patients with progressive pulmonary fibrosis [31]. …

[HTML][HTML] The pathogenesis of cardiac fibrosis: a review of recent progress

K Maruyama, K Imanaka-Yoshida - International journal of molecular …, 2022 - mdpi.com
… Although fibrosis has pathophysiological importance in cardiovascular disease development…
Furthermore, inflammation and fibrosis within perivascular regions decrease the tissue

Ligamentum flavum fibrosis and hypertrophy: molecular pathways, cellular mechanisms, and future directions

C Sun, H Zhang, X Wang, X Liu - The FASEB Journal, 2020 - Wiley Online Library
… Subsequently, this repeated micro-injury induces chronic inflammation and the development
of tissue fibrosis, ultimately resulting in LF hypertrophy.Histologically, the degeneration of …

[HTML][HTML] Current approaches targeting the wound healing phases to attenuate fibrosis and scarring

A El Ayadi, JW Jay, A Prasai - International journal of molecular sciences, 2020 - mdpi.com
… However, prolongation in the inflammatory phase gives rise to fibrotic tissues that can manifest
as … that may be worth pursuing to gain better insights into the pathophysiology of fibrosis. …

Inflammatory mediators and renal fibrosis

XM Meng - Renal Fibrosis: Mechanisms and Therapies, 2019 - Springer
… may help to clarify the pathway from renal inflammation to fibrosis. The current chapter
focuses on key inflammatory cell types and pathways linking renal inflammation with fibrosis. …

[HTML][HTML] The role of pathological aging in cardiac and pulmonary fibrosis

LA Murtha, M Morten, MJ Schuliga… - Aging and …, 2019 - ncbi.nlm.nih.gov
… Furthermore, inflammaging and its sustained increase of inflammatory markers, which at …
, and the low grade chronic inflammation which sustains the persistent fibrosis of CVD and IPF. …

[HTML][HTML] Obesity and obesity-induced inflammatory disease contribute to atherosclerosis: a review of the pathophysiology and treatment of obesity

RJ Henning - American journal of cardiovascular disease, 2021 - ncbi.nlm.nih.gov
… aggregation, vascular endothelial dysfunction, thrombosis, and fibrosis. In order to reduce
obesity and obesity-induced inflammation, therapies including diet, medications, and bariatric …

The intestinal tissue homeostasis–the role of extracellular matrix remodeling in inflammatory bowel disease

JH Mortensen, M Lindholm, LL Langholm… - Expert Review of …, 2019 - Taylor & Francis
… matrix remodeling in IBD in terms of pathophysiology, in relation to clinically important …
In reality, however, the process of inflammation and fibrosis is dynamic and intertwined and …