A view on drug resistance in cancer

N Vasan, J Baselga, DM Hyman - Nature, 2019 - nature.com
… of drug resistance, which … to drug resistance that are based on earlier detection of tumours
permitting cancer interception; adaptive monitoring during therapy; the addition of novel drugs

Recent updates on drug resistance in Mycobacterium tuberculosis

R Singh, SP Dwivedi, US Gaharwar… - Journal of applied …, 2020 - academic.oup.com
… basis for evolution of Mtb drug resistance. This narrative and traditional … and drug resistance
mechanisms in Mtb. The aim of this review is to provide recent updates on drug resistance

[HTML][HTML] Drug resistance and combating drug resistance in cancer

X Wang, H Zhang, X Chen - Cancer drug resistance, 2019 - ncbi.nlm.nih.gov
… In this review, intrinsic and acquired resistance will be discussed. In addition, new … of drug
resistance will be reviewed. Particularly, we will highlight roles of ATP in drug resistance by …

[HTML][HTML] HIV-1 drug resistance testing is essential for heavily-treated patients switching from first-to second-line regimens in resource-limited settings: evidence from …

D Takou, J Fokam, G Teto, MM Santoro… - BMC infectious …, 2019 - Springer
… HIV drug resistance (HIVDR), which is driven by delayed detection of virological failure and
accumulation of drug resistant … This later increases cases of new HIV-infections with resistant

[HTML][HTML] Anticancer drug resistance: An update and perspective

R Nussinov, CJ Tsai, H Jang - Drug Resistance Updates, 2021 - Elsevier
… In the current review we ask: Are drug resistance mechanisms that emerge following … lead
to the same drug resistance modality? This question portends critical drug treatment decisions (…

Rates of HIV-1 virological suppression and patterns of acquired drug resistance among fisherfolk on first-line antiretroviral therapy in Uganda

J Omooja, M Nannyonjo, G Sanyu… - Journal of …, 2019 - academic.oup.com
… on ART and this form of HIV drug resistance (HIVDR) may occur … plasma drug concentrations
or the use of less efficacious drugresistance testing were vital in monitoring first-line ART. …

Modeling the mechanism pathways of first line drug in Tuberculosis using Petri nets

GP Singh, M Jha, M Singh, Naina - International Journal of System …, 2020 - Springer
… The two main problems in prevention tuberculosis is the late and incomplete diagnosis
and the drug resistance of the First Line and Second Line Drugs. In this paper, we have …

Challenges and opportunities in cancer drug resistance

RA Ward, S Fawell, N Floc'h, V Flemington… - Chemical …, 2020 - ACS Publications
… These observations led to additional drug discovery efforts to target the drug resistance
L119M mutation. In addition, a wider range of drug resistant mutations were observed such as …

Mechanisms of drug resistance in acute myeloid leukemia

J Zhang, Y Gu, B Chen - OncoTargets and therapy, 2019 - Taylor & Francis
… the mechanisms of drug resistance in AML is very active. This article will elaborate on the
main mechanisms of drug resistance currently being studied, including drug resistance-related …

[HTML][HTML] … of whole-genome analysis of an extensively drug-resistant Mycobacterium tuberculosis clinical isolate with bedaquiline, linezolid and clofazimine resistance …

JM Kabahita, J Kabugo, F Kakooza, I Adam… - Antimicrobial Resistance …, 2022 - Springer
first line and second line drugs whereas MX and KA catered for sensitivity and resistance to
both first- and second-line drugs. … drug susceptibility test results that showed the first instance …