… genetically mediated forms of frontotemporal dementia have spearheaded this enterprise. …
of the frontotemporal dementias, motivated by our emerging understanding of the mechanisms …

… of neuroinflammatory mechanisms in FTD and describes how advances in our understanding
of these mechanisms, in FTD as well as in other neurodegenerative diseases, might …

… This is the case for early frontotemporal dementia (FTD) and bipolar disorder. In its initial
stages, FTD is characterized by behavioral or language disturbances in the absence of …

… Frontotemporal dementia (… disease mechanism in FTD and ALS. Further studies into the
normal function of many of these proteins are required and will help uncover the mechanisms …

… of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). The main pathogenic
mechanisms in … Additionally, abnormalities in different downstream cellular mechanisms, …

… genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
The proposed disease mechanisms include loss of C9orf72 function and gain of toxicity from …

… We discuss the emerging disease pathways that have emerged from these in vivo models
and how this has shaped our understanding of disease mechanisms underpinning FTD. We …

… Frontotemporal dementias (FTDs) encompass several disorders commonly characterized by
progressive frontotemporal lobar degeneration and dementia… The complex mechanisms that …

… in these diseases and discuss recent evidence for converging mechanisms. This review …
to argue that lysosomal failure is a primary mechanism of disease, rather than merely reflecting …

… (ALS) and frontotemporal dementia (FTD). There are three main disease mechanisms: loss
of … While many of the downstream mechanisms have been identified, the specific pathogenic …