[HTML][HTML] Next-generation sequencing technology: current trends and advancements

H Satam, K Joshi, U Mangrolia, S Waghoo, G Zaidi… - Biology, 2023 - mdpi.com
… our knowledge of genome structure, function, and dynamics. This groundbreaking …
sequencing, leading to the emergence of three generations of sequencing technologies (Figure 1). …

High-throughput DNA sequencing technologies for water and wastewater analysis

AWY Chan, J Naphtali, HE Schellhorn - Science progress, 2019 - journals.sagepub.com
… Before taxonomic and functional analysis, WMS reads are quality-trimmed and -filtered
for adapters and low-quality base calls based on the phred scoring system. This process is …

[HTML][HTML] Genomic analysis in the age of human genome sequencing

T Lappalainen, AJ Scott, M Brandt, IM Hall - Cell, 2019 - cell.com
… -genome sequencing, genome-wide functional genomic approaches for predicting and
measuring variant functional … The development of high-throughput sequencing technologies has …

Next-generation sequencing technologies: An overview

T Hu, N Chitnis, D Monos, A Dinh - Human Immunology, 2021 - Elsevier
… Tertiary NGS analysis involves variant annotation and interpretation. This analysis usually
involves functional annotation of discovered variants (eg, SNP, INDEL, and CNV interpretation…

Recent advancement in next-generation sequencing techniques and its computational analysis

K Raza, S Ahmad - International Journal of Bioinformatics …, 2019 - inderscienceonline.com
… been developed to cater high demand for cheaper as well as faster sequencing technology.
… of DNA regions which interact with regulatory proteins in functional regulation of gene …

[HTML][HTML] Bioinformatics and computational tools for next-generation sequencing analysis in clinical genetics

R Pereira, J Oliveira, M Sousa - Journal of clinical medicine, 2020 - mdpi.com
… group of cyclic-array sequencing technologies (reviewed by [6]). … for the analysis of genetic
variation and biological function that … of Illumina sequencing is based on the sequencing-by-…

Next-generation sequencing and emerging technologies

KR Kumar, MJ Cowley, RL Davis - Seminars in thrombosis and …, 2024 - thieme-connect.com
… Genetic sequencing technologies are evolving at a rapid pace with major implications for
research … As the sequencing rate is a function of nucleotide addition by the polymerase, PacBio …

[HTML][HTML] Alternative splicing: Human disease and quantitative analysis from high-throughput sequencing

W Jiang, L Chen - Computational and structural biotechnology journal, 2021 - Elsevier
technologies may resolve those issues in the near future. 1) Long-read sequencing, SMRT
and Nanopore sequencing technologies… Those technologies have been proven applicable in …

Nanopore sequencing: Review of potential applications in functional genomics

N Kono, K Arakawa - Development, growth & differentiation, 2019 - Wiley Online Library
… led by various measurement technologies, and increased throughput has developed omics
analysis. The development of massively parallel sequencing technology has enabled access …

[HTML][HTML] Applications of high-throughput sequencing to analyze and engineer ribozymes

Y Yokobayashi - Methods, 2019 - Elsevier
… by Sanger sequencing. The advent of high-throughput sequencing technologies, however,
… should provide rich information on sequence-function relationship of the parental ribozyme. …