[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib
Y Kim, SH Lee, JS Ahn, MJ Ahn, K Park… - Cancer Research and …, 2019 - ncbi.nlm.nih.gov
… evaluate the pattern of clinical use of three EGFR TKIs (afatinib, gefitinib, and erlotinib). We
found that gefitinib was more commonly used than erlotinib or afatinib in Korea, especially for …
found that gefitinib was more commonly used than erlotinib or afatinib in Korea, especially for …
Clinical outcomes of gefitinib and erlotinib in patients with NSCLC harboring uncommon EGFR mutations: A pooled analysis of 438 patients
C Wang, K Zhao, S Hu, W Dong, Y Gong, M Li, C Xie - Lung Cancer, 2022 - Elsevier
… [23], [24], [25], [26], [27], [28], [29], [30] In this study, we explored the outcomes of some
relatively frequent single uncommon EGFR mutations, and differences in efficacy and prognosis …
relatively frequent single uncommon EGFR mutations, and differences in efficacy and prognosis …
[HTML][HTML] A comparative study on erlotinib & gefitinib therapy in non-small cell lung carcinoma patients
P Thomas, B Vincent, C George… - Indian Journal of …, 2019 - journals.lww.com
… The adverse reactions most commonly observed during EGFRI (erlotinib and gefitinib) … be
EGFR mutated, 22.5 per cent were non-mutated and others were not tested for EGFR mutation …
EGFR mutated, 22.5 per cent were non-mutated and others were not tested for EGFR mutation …
[HTML][HTML] Pembrolizumab in combination with erlotinib or gefitinib as first-line therapy for advanced NSCLC with sensitizing EGFR mutation
JCH Yang, SM Gadgeel, LVD Sequist, CL Wu… - Journal of Thoracic …, 2019 - Elsevier
… /IV EGFR-mutant NSCLC were treated with pembrolizumab 2 mg/kg intravenously every 3
weeks plus oral erlotinib 150 mg daily in cohort E or oral gefitinib … The most frequent treatment-…
weeks plus oral erlotinib 150 mg daily in cohort E or oral gefitinib … The most frequent treatment-…
[HTML][HTML] Comparison of effectiveness of Gefitinib, Erlotinib, and Afatinib in advanced non-small cell lung cancer patients with EGFR mutation positive in Indonesian …
N Sutandyo, A Hanafi, M Jayusman - Chinese journal of lung …, 2019 - ncbi.nlm.nih.gov
… The most common mutations were the deletion in exon 19 and … provides evidence that
gefitinib, erlotinib, and afatinib have similar effectiveness in advance stage EGFR mutation lung …
gefitinib, erlotinib, and afatinib have similar effectiveness in advance stage EGFR mutation lung …
… factor receptor (EGFR) T790M mutation among first‐line gefitinib, erlotinib and afatinib‐treated non‐small cell lung cancer patients with activating EGFR mutations
YT Lin, JS Chen, WY Liao, CC Ho… - … Journal of Cancer, 2019 - Wiley Online Library
… Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) commonly are …
including impacts on secondary EGFR T790M mutation, the most frequent EGFR-TKI resistance …
including impacts on secondary EGFR T790M mutation, the most frequent EGFR-TKI resistance …
[HTML][HTML] Tyrosine kinase inhibitors for the treatment of EGFR mutation-positive non–small-cell lung cancer: a clash of the generations
R Shah, JF Lester - Clinical lung cancer, 2020 - Elsevier
… Both gefitinib and erlotinib have been … with gefitinib in 319 treatment-naive patients (160
randomized to afatinib and 159 to gefitinib) with NSCLC harboring common EGFR mutations (…
randomized to afatinib and 159 to gefitinib) with NSCLC harboring common EGFR mutations (…
[HTML][HTML] … different central nervous system efficacy among gefitinib, erlotinib and afatinib in patients with epidermal growth factor receptor mutation-positive non-small …
HA Jung, SY Woo, SH Lee, JS Ahn… - Translational Lung …, 2020 - ncbi.nlm.nih.gov
… with gefitinib or erlotinib after adjusting for both EGFR mutation … among the three most
commonly available TKIs. Therefore, … most commonly available first- or second-generation EGFR …
commonly available TKIs. Therefore, … most commonly available first- or second-generation EGFR …
[HTML][HTML] Recent advances on the role of EGFR tyrosine kinase inhibitors in the management of NSCLC with uncommon, non exon 20 insertions, EGFR mutations
… largely concentrated on common EGFR mutations, reflecting … analysis of compound EGFR
mutations (two uncommon mutations) … to different EGFR TKIs (erlotinib, gefitinib, afatinib, and …
mutations (two uncommon mutations) … to different EGFR TKIs (erlotinib, gefitinib, afatinib, and …
Repeat biopsy procedures and T790M rates after afatinib, gefitinib, or erlotinib therapy in patients with lung cancer
K Lee, Y Kim, HA Jung, SH Lee, JS Ahn, MJ Ahn… - Lung cancer, 2019 - Elsevier
… We performed EGFR mutation tests by using the peptide nucleic acid … EGFR T790 M mutation
is the most common resistance mechanism to first-generation EGFR-TKIs (gefitinib, erlotinib…
is the most common resistance mechanism to first-generation EGFR-TKIs (gefitinib, erlotinib…
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