Ultrasound imaging of gene expression in mammalian cells

A Farhadi, GH Ho, DP Sawyer, RW Bourdeau… - Science, 2019 - science.org
… To address this limitation, we introduce mammalian acoustic reporter genes. … the expression
of ARGs in mammalian cells to enable ultrasound imaging of mammalian gene expression. …

Optimization of protein expression in mammalian cells

M Hunter, P Yuan, D Vavilala… - Current protocols in …, 2019 - Wiley Online Library
… usage on gene expression. Specifically, research has demonstrated that gene expression
levels correlate with the use of optimal codons, codons that have the highest tRNA gene

Pressure-induced changes on the morphology and gene expression in mammalian cells

K Okamoto, TM Watanabe, M Horie… - Biology …, 2021 - journals.biologists.com
… on cells, we observed the morphology and gene expression of mouse embryonic fibroblasts
(MEFs) and mouse embryonic stem (ES) cellsgene expression analysis. We found that …

[HTML][HTML] Manipulating gene expression levels in mammalian cell factories: an outline of synthetic molecular toolboxes to achieve multiplexed control

P Eisenhut, N Marx, G Borsi, M Papež, C Ruggeri… - New …, 2023 - Elsevier
… , synthetic biology tools inspired by naturally occurring gene … of gene expression. In this
review, we discuss various molecular tools that have been established in mammalian cell lines …

Gene expression across mammalian organ development

M Cardoso-Moreira, J Halbert, D Valloton, B Velten… - Nature, 2019 - nature.com
gene expressiongene expression and the extent of purifying selection gradually decrease
during development, whereas the amount of positive selection and expression of new genes

Controlling gene expression in mammalian cells using multiplexed conditional guide RNAs for Cas12a

L Oesinghaus, FC Simmel - Angewandte Chemie International …, 2021 - Wiley Online Library
… coli cells, 11f while Lin et al. demonstrated activation of Cas9 gRNAs in mammalian cells
switchable gRNAs for gene expression in mammalian cells is challenging due to the large …

Developmental gene expression differences between humans and mammalian models

M Cardoso-Moreira, I Sarropoulos, B Velten, M Mort… - Cell reports, 2020 - cell.com
… Developmental gene expression profiles provide a window into the genes underlying organ
development and a direct means to compare them across species. We use a transcriptomic …

A human cell atlas of fetal gene expression

J Cao, DR O'day, HA Pliner, PD Kingsley, M Deng… - Science, 2020 - science.org
cell atlases of gene expression and chromatin accessibility in fetal tissues. For gene expression,
cells. We leveraged the literature and other atlases to identify and annotate hundreds of …

Silencing of transgene expression in mammalian cells by DNA methylation and histone modifications in gene therapy perspective

SY Alhaji, SC Ngai, S Abdullah - Biotechnology and Genetic …, 2019 - Taylor & Francis
gene expression and chromatin architecture without altering the DNA structure. It is a
phenomenon that occurs in mammalian cells and is necessary for cell … against foreign genes (…

Analytical distributions for detailed models of stochastic gene expression in eukaryotic cells

Z Cao, R Grima - Proceedings of the National Academy of …, 2020 - National Acad Sciences
… (A) Using parameters typical of mammalian cells, we find that our theory agrees well with
simulations for d / d p = 30 , is acceptable for d / d p = 10 , and performs poorly for d / d p = 5 ; …