Gastric cancer

EC Smyth, M Nilsson, HI Grabsch, NCT van Grieken… - The Lancet, 2020 - thelancet.com
Genetics of gastric cancer … adenocarcinoma with proximal polyposis of the stomach
has been shown to be associated with point mutations in the APC promotor 1B gene. …

The landscape of 8q24 cytoband in gastric cancer

V Larios-Serrato, HA Valdez-Salazar… - Oncology …, 2024 - spandidos-publications.com
… such as the MYC gene, which induces expression of selective genes to promote cell growth
… assist in identifying genes associated with GC. In the present review, 12 genes present in …

Histological and mutational profile of diffuse gastric cancer: current knowledge and future challenges

J Garcia‐Pelaez, R Barbosa‐Matos, I Gullo… - Molecular …, 2021 - Wiley Online Library
… , reflecting morphological, molecular and genetic diversity. Diffuse gastric cancer (DGC)
and intestinal gastric cancer (IGC) are the major … Normal gastric mucosa gene expression …

Identification of pivotal genes associated with the prognosis of gastric carcinoma through integrated analysis

Z Ma, J Xu, L Ru, W Zhu - Bioscience Reports, 2021 - portlandpress.com
gastric cancer (GC) during its early period remains greatly difficult. Our analysis was performed
to detect core genes … of co-expressed genes for common genes to improve the capability …

[HTML][HTML] Molecular classification of gastric adenocarcinoma

Q Wang, G Liu, C Hu - Gastroenterology Research, 2019 - ncbi.nlm.nih.gov
… After comparing gene expression patterns among 248 gastric tumors (Singaporean patients
from the National Cancer Centre and hospitals of the National Healthcare Group, Australian …

Molecular alterations in gastric preneoplastic lesions and early gastric cancer

S Battista, MR Ambrosio, F Limarzi, G Gallo… - International journal of …, 2021 - mdpi.com
… Regarding molecular alterations, Tsukashita, in 2001 [36], evaluated the histogenesis of
gastric adenocarcinoma by MUC gene expression in eighty intramucosal gland-forming tumors. …

Mapping the genomic diaspora of gastric cancer

KG Yeoh, P Tan - Nature reviews cancer, 2022 - nature.com
… , revealed driver alterations in genes such as ERBB2, FGFR2… in normal gastric tissues,
metaplasia, primary carcinoma and … cancer gene discovery by pinpointing new GC-related genes

Meta-analysis of genome-wide association studies and functional assays decipher susceptibility genes for gastric cancer in Chinese populations

C Yan, M Zhu, Y Ding, M Yang, M Wang, G Li, C Ren… - Gut, 2020 - gut.bmj.com
… of genetic loci have been associated with gastric cancer (GC) … We aimed to identify new
susceptibility genes and elucidate … the genetic variants at 5p13.1 and 10q23.33 influence gastric

Identification of specific modules and hub genes associated with the progression of gastric cancer

C Gong, Y Hu, M Zhou, M Yao, Z Ning, Z Wang… - …, 2019 - academic.oup.com
… A PPI network was carried out on genes of the gastric cancer progression-related module
(GCPR) based on the string-DB database (Version:10.0) (http://www.string-db.com). To …

Gastric cancer: epidemiology, risk factors, classification, genomic characteristics and treatment strategies

J Machlowska, J Baj, M Sitarz, R Maciejewski… - International journal of …, 2020 - mdpi.com
… , where both environmental and genetic factors can have an … of gastric carcinomas are
detected at the age of 45 or younger. Early-onset gastric cancer is a good model to study genetic