Safety and tolerability of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in oncology
RR Shah, DR Shah - Drug safety, 2019 - Springer
… Hepatic failure and hepatorenal syndrome, including fatal cases, can occur with erlotinib
treatment in patients with normal hepatic function; the risk of hepatic toxicity is increased in …
treatment in patients with normal hepatic function; the risk of hepatic toxicity is increased in …
Effect of metformin plus tyrosine kinase inhibitors compared with tyrosine kinase inhibitors alone in patients with epidermal growth factor receptor–mutated lung …
O Arrieta, F Barrón, MÁS Padilla, A Avilés-Salas… - JAMA …, 2019 - jamanetwork.com
… Patients in the EGFR-TKIs group received treatment with erlotinib hydrochloride, afatinib
dimaleate, or gefitinib at standard dosage according to physician preference. Patients in the …
dimaleate, or gefitinib at standard dosage according to physician preference. Patients in the …
[HTML][HTML] … therapy: Hyaluronic acid modified, epidermal growth factor receptor targeted, pH sensitive lipid-polymer hybrid nanoparticles for the delivery of erlotinib plus …
J Pang, H Xing, Y Sun, S Feng, S Wang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
… endothelial growth factor (VEGF) and epidermal growth factor … Epidermal growth factor
receptor (EGFR) mutation-positive … Erlotinib (ERL), one of EGFR tyrosine kinase inhibitors (TKIs)…
receptor (EGFR) mutation-positive … Erlotinib (ERL), one of EGFR tyrosine kinase inhibitors (TKIs)…
Bevacizumab plus erlotinib versus erlotinib alone in Japanese patients with advanced, metastatic, EGFR-mutant non-small-cell lung cancer (NEJ026): overall survival …
Y Kawashima, T Fukuhara, H Saito… - The Lancet …, 2022 - thelancet.com
… treatment with epidermal growth factor receptor tyrosine-kinase inhibitors (eg, erlotinib), …
bevacizumab plus erlotinib significantly prolonged progression-free survival compared with …
bevacizumab plus erlotinib significantly prolonged progression-free survival compared with …
… to the individual variations of erlotinib steady state trough concentration, treatment outcomes, and adverse reactions in epidermal growth factor receptor–mutated non …
D Liao, Z Liu, Y Zhang, N Liu, D Yao, L Cao… - Frontiers in …, 2020 - frontiersin.org
… Patients with advanced NSCLC who were treated with oral erlotinib at a standard dose of …
; 2) unmodified dosage of erlotinib during the treatment period. This study was designed and …
; 2) unmodified dosage of erlotinib during the treatment period. This study was designed and …
RELAY, ramucirumab plus erlotinib versus placebo plus erlotinib in patients with untreated, epidermal growth factor receptor mutation-positive, metastatic non-small …
… RAM + ERL offers a tolerable and effective option for the first-line treatment of epidermal
growth factor receptor exon 19 deletion or exon 21 (L858R) mutation-positive metastatic non-…
growth factor receptor exon 19 deletion or exon 21 (L858R) mutation-positive metastatic non-…
A comparative study on erlotinib & gefitinib therapy in non-small cell lung carcinoma patients
P Thomas, B Vincent, C George… - Indian Journal of …, 2019 - journals.lww.com
… growth factor receptor (EGFR) have been evaluated in patients with advanced non-small cell
lung cancer (NSCLC). Erlotinib … patients taking erlotinib and gefitinib for treating NSCLC in …
lung cancer (NSCLC). Erlotinib … patients taking erlotinib and gefitinib for treating NSCLC in …
… patients with untreated metastatic epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma receiving first-line erlotinib and bevacizumab combination …
CC Wang, LC Chiu, PH Tung, SCH Kuo, CH Chu… - Oncology and …, 2021 - Springer
… erlotinib treatment [34]. In the previous three clinical studies (JO25567, NEJ026, and RELAY
trials), only a few patients had plasma ctDNA for EGFR-T790M mutation tests (NEJ026), but …
trials), only a few patients had plasma ctDNA for EGFR-T790M mutation tests (NEJ026), but …
Adjuvant treatment with tyrosine kinase inhibitors in epidermal growth factor receptor mutated non-small-cell lung carcinoma patients, past, present and future
… cancer treatments for a subtype known as non-small cell lung cancer with a special mutation
of epidermal growth factor … therapy with erlotinib, and in 36 patients who concluded erlotinib …
of epidermal growth factor … therapy with erlotinib, and in 36 patients who concluded erlotinib …
Dual EGFR blockade with cetuximab and erlotinib combined with anti-VEGF antibody bevacizumab in advanced solid tumors: a phase 1 dose escalation triplet …
… Angiogenesis and activation of the epidermal growth factor (EGFR) pathway play an …
with erlotinib and cetuximab. We also evaluated the anti-tumor efficacy of this treatment per …
with erlotinib and cetuximab. We also evaluated the anti-tumor efficacy of this treatment per …