Epidermal growth factor receptor inhibitors as potential anticancer agents: An update of recent progress
… Epidermal growth factor receptor (EGFR) is a vital intermediate in cell signaling pathway …
Here, we have discussed anti-cancer activity and growth factor receptor inhibitory activity …
Here, we have discussed anti-cancer activity and growth factor receptor inhibitory activity …
Dermatologic adverse events associated with selective fibroblast growth factor receptor inhibitors: overview, prevention, and management guidelines
ME Lacouture, V Sibaud, MJ Anadkat… - The …, 2021 - academic.oup.com
… Schematic representation of dermatologic adverse events associated with fibroblast growth
factor receptor inhibition. Suggested dose modifications for dermatologic adverse events: …
factor receptor inhibition. Suggested dose modifications for dermatologic adverse events: …
Fibroblast growth factor receptors (FGFRs): structures and small molecule inhibitors
S Dai, Z Zhou, Z Chen, G Xu, Y Chen - Cells, 2019 - mdpi.com
Fibroblast growth factor receptors (FGFRs) are a family of receptor tyrosine kinases
expressed on the cell membrane that play crucial roles in both developmental and adult cells. …
expressed on the cell membrane that play crucial roles in both developmental and adult cells. …
Multicenter phase I study of erdafitinib (JNJ-42756493), oral pan-fibroblast growth factor receptor inhibitor, in patients with advanced or refractory solid tumors
R Bahleda, A Italiano, C Hierro, A Mita… - Clinical Cancer …, 2019 - AACR
… , a fibroblast growth factor receptor 1–3 kinase inhibitor, in … genetic alterations in fibroblast
growth factor receptors: results of a … , an inhibitor of fibroblast growth factor receptor (FGFR), in …
growth factor receptors: results of a … , an inhibitor of fibroblast growth factor receptor (FGFR), in …
Fibroblast growth factor receptors as treatment targets in clinical oncology
M Katoh - Nature reviews Clinical oncology, 2019 - nature.com
… , and the benefits of FGFR inhibitors have been demonstrated in … the clinical experience
with FGFR inhibitors to date, and … FGFR inhibitors in combination regimens with other agents. …
with FGFR inhibitors to date, and … FGFR inhibitors in combination regimens with other agents. …
Computational modeling of novel quinazoline derivatives as potent epidermal growth factor receptor inhibitors
… inhibitors. The second and third generation EGFR inhibitors are referred to as irreversible
inhibitors (… of quinazoline-based kinase inhibitors for mutant epidermal growth factor receptors. …
inhibitors (… of quinazoline-based kinase inhibitors for mutant epidermal growth factor receptors. …
A review on progression of epidermal growth factor receptor (EGFR) inhibitors as an efficient approach in cancer targeted therapy
The identification of molecular agents inhibiting specific functions in cancer cells progression
is considered as one of the most successful plans in cancer treatment. The epidermal …
is considered as one of the most successful plans in cancer treatment. The epidermal …
[PDF][PDF] Review on epidermal growth factor receptor (EGFR) structure, signaling pathways, interactions, and recent updates of EGFR inhibitors
… growth factor receptor (EGFR) belongs to the ERBB family of tyrosine kinase receptors. EGFR
… interaction, and the progress in the development of EGFR inhibitors have been explored. …
… interaction, and the progress in the development of EGFR inhibitors have been explored. …
[HTML][HTML] Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication
SARS-CoV-2 infections are rapidly spreading around the globe. The rapid development of
therapies is of major importance. However, our lack of understanding of the molecular …
therapies is of major importance. However, our lack of understanding of the molecular …
[HTML][HTML] Vascular endothelial growth factor receptor (VEGFR-2)/KDR inhibitors: medicinal chemistry perspective
SJ Modi, VM Kulkarni - Medicine in Drug Discovery, 2019 - Elsevier
… growth factors such as PLGF, EGF, cytokines, etc. [58]. Upregulation and activation of growth
factor receptors … This activated receptor leads to endothelial cell sprouting, increase in the …
factor receptors … This activated receptor leads to endothelial cell sprouting, increase in the …
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