… In this Review, we discuss the therapeutic potential of targeting mitochondria in patients
with cardiovascular disease, examine the obstacles that have restrained the development of …

… of heart failure but cannot save dead heart cells, clinicians began to look for a new way to
treat heart failure after MI. Heart transplantation remains the only cure for heart failure patients, …

… heart failure has been continuously explored in the past ten years, the mortality and readmission
rate of heart failure … study of gut microbiota and heart failure attracts particular attention. …

… NPs; and finally, (viii) we will provide a contemporary perspective of the challenges of
harnessing the therapeutic potential of NPs in HF that need to be addressed for future success. …

… T2DM accounts for 90% to 95% of all diabetes mellitus cases, 4 for this reason, this
review will focus on pharmacological treatments for T2DM and their impact on heart failure (HF) …

… A major obstacle that hampers development of new therapeutics in heart failure is the
pathophysiologic heterogeneity of the disease. The clinical syndrome of heart failure can be …

… Outcomes of several ongoing prospective studies of SGLT‐2 inhibitors in HF (Figure 3) are
needed to fully evaluate the therapeutic potential of SGLT‐2 inhibitors in HF, with and without …

… the age of 20 years have heart failure (HF). This disorder continues to be a significant
cause of morbidity and mortality in developed nations, and ischemic heart disease (IHD) is the …

… in heart failure and arrhythmia. The hawthorn extract demonstrates efficacy in the treatment
of heart failure, … in wine, has shown efficacy against heart failure in isolated tissues or organs, …

Heart failure (HF) is a global public health problem with high morbidity and mortality. A large
number of studies have shown that HF is caused by severe energy metabolism disorders, …