Molecular mechanisms of iron and heme metabolism
… Senescent or damaged RBCs are degraded by RES macrophages, in which heme oxygenase
degrades heme, thereby liberating iron for export by ferroportin into circulation. Under …
degrades heme, thereby liberating iron for export by ferroportin into circulation. Under …
Heme-oxygenase-1
MM Facchinetti - Antioxidants & Redox Signaling, 2020 - liebertpub.com
… This Forum issue “Heme Oxygenase” (HO) includes original research articles and reviews …
in cells and tissues, and address the molecular and cellular mechanisms through which HO-1 …
in cells and tissues, and address the molecular and cellular mechanisms through which HO-1 …
[HTML][HTML] Heme, heme oxygenase, and endoplasmic reticulum stress—a new insight into the pathophysiology of vascular diseases
… induced endoplasmic reticulum stress (HIERS) participates in the pathogenesis of
vascular disorders and highlights recent discoveries in the molecular mechanisms of HO-mediated …
vascular disorders and highlights recent discoveries in the molecular mechanisms of HO-mediated …
[HTML][HTML] Role of heme oxygenase as a modulator of heme-mediated pathways
JC Duvigneau, H Esterbauer, AV Kozlov - Antioxidants, 2019 - mdpi.com
… The circadian clock is an oscillating molecular mechanism consisting of clock genes regulated
as loops at the transcriptional and translational level, which regulates a number of cellular …
as loops at the transcriptional and translational level, which regulates a number of cellular …
[HTML][HTML] Heme oxygenase-1 signaling and redox homeostasis in physiopathological conditions
V Consoli, V Sorrenti, S Grosso, L Vanella - Biomolecules, 2021 - mdpi.com
… the actual HO-1 mechanism of action responsible for his cytoprotective effects, instead it
became possible to address the molecular mechanism involved in programmed apoptosis …
became possible to address the molecular mechanism involved in programmed apoptosis …
Heme oxygenases: Cellular multifunctional and protective molecules against UV‐induced oxidative stress
SD Chen, XY Wang, MF Nisar, M Lin… - … medicine and cellular …, 2019 - Wiley Online Library
… It is well known that UVA is an oxidative agent, so we mainly focused on the molecular
mechanism of UVA which actives the antioxidant signal pathways which affect the transactivation …
mechanism of UVA which actives the antioxidant signal pathways which affect the transactivation …
Heme oxygenase 1 in vertebrates: friend and foe
RCM Costa Silva, LHT Correa - Cell biochemistry and biophysics, 2022 - Springer
… Heme oxygenase-1 (HO-1) is the inducible … heme degradation and generation of byproducts
with antioxidant properties highlights the importance of HO-1 as a response mechanism …
with antioxidant properties highlights the importance of HO-1 as a response mechanism …
[HTML][HTML] Nuclear localization of heme oxygenase-1 in pathophysiological conditions: Does it explain the dual role in cancer?
M Mascaró, EN Alonso, EG Alonso, E Lacunza… - Antioxidants, 2021 - mdpi.com
… However, the exact molecular mechanisms by which it does so remain unknown. It is highly
recognized that HO-1 protein does not have a DNA-binding consensus sequence [10]. One …
recognized that HO-1 protein does not have a DNA-binding consensus sequence [10]. One …
[HTML][HTML] Significance of heme and heme degradation in the pathogenesis of acute lung and inflammatory disorders
SW Ryter - International Journal of Molecular Sciences, 2021 - mdpi.com
… Molecular genetics characterizations have revealed two distinct molecular species: heme
oxygenase-1 (HO-1) and heme … mammals is catalyzed by microsomal heme oxygenase (HO) […
oxygenase-1 (HO-1) and heme … mammals is catalyzed by microsomal heme oxygenase (HO) […
[HTML][HTML] Heme oxygenase-1: an anti-inflammatory effector in cardiovascular, lung, and related metabolic disorders
SW Ryter - Antioxidants, 2022 - mdpi.com
… molecular oxygen (O 2 ) and electrons donated from NADPH cytochrome p-450 reductase [7].
The ferrous heme … subsequent autocatalytic cleavage of the heme molecule [7]. HO activity …
The ferrous heme … subsequent autocatalytic cleavage of the heme molecule [7]. HO activity …
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