Identifying novel biomarkers in hepatocellular carcinoma by weighted gene co‐expression network analysis

B Li, K Pu, X Wu - Journal of cellular biochemistry, 2019 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a highly malignant tumor found in the bile duct epithelial
cells, and the second most common tumor of the liver. However, the pivotal roles of most …

Construction and comprehensive analysis of a ceRNA network to reveal potential prognostic biomarkers for hepatocellular carcinoma

J Long, Y Bai, X Yang, J Lin, X Yang, D Wang… - Cancer cell …, 2019 - Springer
… (ceRNA) network and have attracted growing attention. The present study explored the
regulatory mechanisms and functional roles of lncRNAs as ceRNAs in hepatocellular carcinoma (…

Integrated bioinformatic analysis identifies networks and promising biomarkers for hepatitis B virus‐related hepatocellular carcinoma

Y Ji, Y Yin, W Zhang - International Journal of Genomics, 2020 - Wiley Online Library
… as a dominant hazard factor for hepatocellular carcinoma (HCC) and accounts for at least …
network (PPI) was performed. The ten hub genes screened out from the PPI network were …

Identification of lncRNA/circRNA-miRNA-mRNA ceRNA network as biomarkers for hepatocellular carcinoma

S Chen, Y Zhang, X Ding, W Li - Frontiers in genetics, 2022 - frontiersin.org
… Background: Hepatocellular carcinoma (HCC) accounts for the … biomarkers in HCC through
bioinformatic analysis. … The ceRNA network is expected to provide potential biomarkers

The competitive endogenous RNA regulatory network reveals potential prognostic biomarkers for overall survival in hepatocellular carcinoma

Z Zhang, J Li, T He, Y Ouyang, Y Huang, Q Liu… - Cancer …, 2019 - Wiley Online Library
… A lot of potential biomarkers in the current study were found to be closely related to OS in
HCC. Through the ceRNA regulatory network, the potential lncRNA-miRNA-mRNA regulatory …

Biomarkers for the early detection of hepatocellular carcinoma

ND Parikh, AS Mehta, AG Singal, T Block… - … , Biomarkers & …, 2020 - AACR
… III biomarker study) validation of biomarkers. In this review, we highlight promising candidate
biomarkers and biomarkernetwork (EDRN) of the NCI, the discovery and validation of …

Integrated analysis of a competing endogenous RNA network reveals key long noncoding RNAs as potential prognostic biomarkers for hepatocellular carcinoma

J Ye, J Zhang, Y Lv, J Wei, X Shen… - Journal of cellular …, 2019 - Wiley Online Library
… survival of a patient with hepatocellular carcinoma (HCC) remains unclear. … network
constructed. A risk score system was established between lncRNA expression of the ceRNA network

Identification of novel biomarkers for hepatocellular carcinoma using transcriptome analysis

Q Xia, Z Li, J Zheng, X Zhang, Y Di… - Journal of Cellular …, 2019 - Wiley Online Library
… our novel biomarkers. We also integrated miRNA–lncRNA and core targeted gene network
… miRNAs and lncRNAs, which could also be novel biomarkers for hepatocellular carcinoma. …

Biomarkers for immunotherapy of hepatocellular carcinoma

TF Greten, A Villanueva, F Korangy, B Ruf… - Nature Reviews …, 2023 - nature.com
… with advanced-stage hepatocellular carcinoma (HCC). Two … of novel predictive biomarkers
enabling the accurate selection of … We then provide an overview of current biomarker use and …

Screening hub genes as prognostic biomarkers of hepatocellular carcinoma by bioinformatics analysis

Z Zhou, Y Li, H Hao, Y Wang, Z Zhou… - Cell …, 2019 - journals.sagepub.com
… the DEGs in STRING and constructed a PPI network that included 69 nodes and 209 edges
(… In this network, we obtained 15 nodes and 105 edges; these nodes represent 15 genes (all …