… Among the various forms of epigenetic modifications, DNA methylation at the C-5 position of
… of the most well studied epigenetic modifications. DNA methyltransferases (DNMTs) are a …

… The development of low-input technologies charting histone modifications and base-resolution
DNA methylation has unveiled the hidden rules of epigenetic reprogramming during …

… In addition, H3K36me3 recruits DNA methyltransferase 3A (DNMT3A) to methylate DNA,
which is a redundant pathway to inhibit spurious transcription initiation [55]. H3K36me2 is …

… To systematically evaluate the quantitative relationship between histone modifications and
DNA methylation, we used datasets from the Roadmap Epigenomics Project of 35 human …

… Moreover, recognition by the maintenance DNA methyltransferase DNMT1 of H4K20me3
(via … The first H3K9-specific histone methyltransferases identified were the SUV(var)39 family …

… Therefore, the reversible nature of epigenetic modifications … that inhibit DNA methyltransferases
(DNMTs) and histone … -drugs targeting epigenetic modifications. However, most of …

… the deposition of repressive epigenetic modifications at TE loci. … methyltransferases to confer
repressive DNA and chromatin … to the evolution of DNA methyltransferase (DNMT) enzymes, …

… Nowadays, we appreciate that most, if not all, histone modifications are at … DNA
methyltransferases to chromatin, H3K4me3 might protect these genomic regions from inappropriate …

… In this opinion article, we propose that highly conserved DNA methyltransferases (MTases)
represent a unique opportunity for bacterial epigenomic studies. These MTases are rather …

… The 7βS protein hDOT1L is the only enzyme in the human proteome that generates H3K79me,
one of the few histone modifications found within the globular region of the nucleosome (…