… DNA methylation, an epigenetic modification, regulates gene … on DNA methyltransferase
inhibitors. We summarized the mechanisms underlying combination therapy using DNMT …

… are the key connectors, whose changes may cause the gene expression alteration in …
These epigenetic modifications include DNA methylation and demethylation, histone acetylation …

… refered to the inheritable changes of gene expression without alteration in DNA sequence
[3… of epigenetics, epigenetic modifications is divided into DNA methylation, histone methylation …

… focus on histone modifications. Both local and global changes in histone modification profiles
are … Remarkably, Dnmt inhibition with RG108, a DNA methyltransferase inhibitor, blocked …

… Many of the DNA methyltransferases (DNMT) are the enzymes that catalyze this methylation
by epigenetic modifications. The addition of methyl groups into DNA strands changes the …

… of epigenetic drugs including the DNA methyltransferase 1 (… very little is known about epigenetic
modification of RNA and its … the recent developments in epigenetic modifications to RNA. …

… hypomethylated through mutation of DNA methyltransferase MET1. Hypomethylation of genes
… Cytosine DNA methylation is an epigenetic modification that protects genome integrity by …

… epigenetic changes in cancer cells can also affect DNA repair through loss of gene expression
of essential DNA … Combination of PARP and DNA methyltransferase inhibitors has also …

… the role of histone modifications in yeast transcriptional silencing and details our current
understanding of how these marks contribute to the inheritance of epigenetic chromatin states. …

… the background viz., DNA methylation processes, histone modifications, chromatin remodeling
and nc-RNA silencing, resulting in epigenetic modifications and the eventual constitution …