[HTML][HTML] Multi-omics characterization of silent and productive HPV integration in cervical cancer
J Fan, Y Fu, W Peng, X Li, Y Shen, E Guo, F Lu, S Zhou… - Cell Genomics, 2023 - cell.com
… in a cohort of 106 CC patients, we demonstrate that HPV integration leading to expression
of fusion transcripts is associated with CC progression. Further, multidimensional integrative …
of fusion transcripts is associated with CC progression. Further, multidimensional integrative …
Multi‐omics data reveals novel impacts of human papillomavirus integration on the epigenomic and transcriptomic signatures of cervical tumorigenesis
X Zeng, Y Wang, B Liu, X Rao, C Cao… - Journal of Medical …, 2023 - Wiley Online Library
… characterize HPV integrations in the human genome, we analyze HPV-capture sequencing
data to identify HPV integration … -scale multi-omics analysis using genomics data from HPV-…
data to identify HPV integration … -scale multi-omics analysis using genomics data from HPV-…
Multi-omics mapping of human papillomavirus integration sites illuminates novel cervical cancer target genes
M Iden, SW Tsaih, YW Huang, P Liu, M Xiao… - British Journal of …, 2021 - nature.com
… details of a multi-omics approach designed to thoroughly annotate HPV integration events
for … Integration analysis from this study revealed multiple integrations in the lncRNA PVT1, a …
for … Integration analysis from this study revealed multiple integrations in the lncRNA PVT1, a …
Multi-omics characterization of productive HPV integration in cervical cancer.
C Sun, J Fan, Y Fu, W Peng, X Li, Y Shen, D Zou, B Xia… - 2022 - ascopubs.org
… We aim to study the characterization of silent and productive HPV integration in cervical …
papillomavirus (HPV), remains a significant public health problem worldwide. HPV integration …
papillomavirus (HPV), remains a significant public health problem worldwide. HPV integration …
[HTML][HTML] Multi-omics data integration reveals metabolome as the top predictor of the cervicovaginal microenvironment
… against HPV at different stages of cervical neoplasia (Fig 1). Using integrated multi-omics, …
Our integrated analysis further highlighted the importance of this key immune mediator, and …
Our integrated analysis further highlighted the importance of this key immune mediator, and …
[HTML][HTML] Unsupervised multi-omics data integration methods: a comprehensive review
N Vahabi, G Michailidis - Frontiers in genetics, 2022 - frontiersin.org
… , including sequential analysis, CCA- and CIA-based, and factor analysis-based … HPV
integration in clade A7-samples. However, the A9-enriched cluster showed partial HPV integration …
integration in clade A7-samples. However, the A9-enriched cluster showed partial HPV integration …
Integrative Multi-Omics Approaches for Identifying Cervical Cancer Therapeutic Targets
SK Duppala, R Yadala, A Velingkar, P Suravajhala… - bioRxiv, 2022 - biorxiv.org
… of HPV integration sites developed using ICC target genes. … Combining metabolomics and
transcriptomic analysis has … This study confirmed combinational analysis of metabolomics …
transcriptomic analysis has … This study confirmed combinational analysis of metabolomics …
Integration of multi-omics data improves prediction of cervicovaginal microenvironment in cervical cancer
… characterized by a dramatic shift in microbiota composition from Lactobacillus to anaerobes,
has been linked to an increased risk of HPV … present an integrated multi-omics analysis of …
has been linked to an increased risk of HPV … present an integrated multi-omics analysis of …
[HTML][HTML] Multi-omics analysis of overexpressed tumor-associated proteins: gene expression, immunopeptide presentation, and antibody response in oropharyngeal …
T Abou Kors, M Meier, L Mühlenbruch… - Frontiers in …, 2024 - frontiersin.org
… data via N-integration. Correlation analysis was done by integrating ligands from one HLA
… In our cohort CCNA1 was exclusively presented in HPV- tumors. Additionally, IGF2BP3 also …
… In our cohort CCNA1 was exclusively presented in HPV- tumors. Additionally, IGF2BP3 also …
Integrative Multiomics Analyses Identify Molecular Subtypes of Head and Neck Squamous Cell Carcinoma with Distinct Therapeutic Vulnerabilities
P Diao, Y Dai, A Wang, X Bu, Z Wang, J Li, Y Wu… - Cancer …, 2024 - aacrjournals.org
… Collectively, we believe that HPV status might serve as a key integral factor … analysis analyses
to pinpoint the subtype-specific metabolic features and found that IMC3 was characterized …
to pinpoint the subtype-specific metabolic features and found that IMC3 was characterized …
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