Role of cell-to-cell coupling in control of myometrial contractility and labor

RE Garfield - Control of uterine contractility, 2019 - taylorfrancis.com
… These alterations in the extent of structural and functional coupling are … coupling in the
myometrium during pregnancy and parturition. This chapter will review (1) the basis for contraction

The myometrium: from excitation to contractions and labour

S Wray, C Prendergast - Smooth Muscle Spontaneous Activity …, 2019 - Springer
… Excitation-contraction coupling in myometrium. Electrical activity in the form of action potentials
shapes the intracellular calcium signals and thereby modifies force in the uterus. Altering …

A myofibre model for the study of uterine excitation-contraction dynamics

U Goldsztejn, A Nehorai - Scientific reports, 2020 - nature.com
contraction in the myometrium. Moreover, many of the pathways that mediate the effects
of tocolytic and uterotonic drugs have been identified 11 . However, experimental restrictions…

An update on pacemaking in the myometrium

S Wray, MJ Taggart - The Journal of Physiology, 2024 - Wiley Online Library
… Pivotal to understanding the mechanisms of excitation-contraction coupling in the uterus
is the elucidation of processes underlying initiation and propagation of electrical action …

Uterine contractions in rodent models and humans

M Malik, M Roh, SK England - Acta physiologica, 2021 - Wiley Online Library
… , or human myometrial smooth … a contraction. Given these MEA studies and magnetomyography
data showing that multiple pacemaker regions contribute to each contraction in humans, …

Monitoring uterine contractions during labor: current challenges and future directions

RC Young, PS Marinescu, NS Seligman - American Journal of Obstetrics …, 2023 - Elsevier
… Early models proposed wave-like propagation of bioelectrical activity as the sole
mechanism for recruiting the myometrium to participate in the contraction and increase …

The potential role of the cervix in myometrial function

J Vink - Current Opinion in Physiology, 2020 - Elsevier
… The authors concluded that contraction of the cervix might prolong the length of the latent
phase of labor [18, 19, 20, 21, 22, 23, 24]. Although a question still exists as to whether a …

Physiology and Pathology of Contractility of the Myometrium

A Koutras, Z Fasoulakis, A Syllaios, N Garmpis… - in vivo, 2021 - iv.iiarjournals.org
… Progesterone and estrogen have a contraction inhibitory effect, while oxytocin and other …
muscle contraction (4-7). Uterine atony describes the inadequate contraction of the myometrial

[PDF][PDF] Hypothesis: Relaxation Signaling in Human Myometrium

I Buxton, S Barnett - Academia Letters, 2021 - academia.edu
… [41] In myometrium, we have shown that relaxation of oxytocin stimulated contraction by NO
is associated with increased phosphoserine 36842. In addition to phosphorylation of the C-…

The physiological basis with uterine myometrium contractions from electro-mechanical/hormonal myofibril function to the term and preterm labor

FZ Zangeneh, S Hantoushzadeh - Heliyon, 2023 - cell.com
… –contraction coupling in excitable cell of the myometrium It is crucial to evaluate the
excitation-contraction coupling (EC coupling) in the myometrium, … EC coupling is mainly achieved …