… of cell-mediated and humoral adaptive immunity (Pype et al., … of the CD40 with a deregulated
amount of CD40 ligand has … of CD40-CD40L mediated regulation of immune response …

… number of stimulatory and inhibitory immunoreceptors with their natural ligands, have been
identified as gatekeepers of immune responses known as “immune checkpoints”. Stimulatory …

… response. This article will highlight what is known about the biology of the CD40-CD40L axis
in … atherosclerosis while still keeping CD40/CD40L intact for proper immune responses [78]. …

… therapies used to combat neurological disease: those that inhibit CD40–CD40L mediated
neuroinflammation to attenuate the immune response and those that upregulate CD40 …

… immune responses (10, 143, 173). Future research will focus on the critical role of platelets
as an immune cell in the host immune response… particularly via the CD40L/CD40 complex, in …

… A limitation associated with the use of siRNA is the lack of targeting ability and a systemic
block of CD40 could impact the immune system, resulting in such effects as a reduction in the …

… CD40L plays a major role in immune response and is a major therapeutic target for …
CD40 simultaneously bind to CD40L. It is unclear if α5β1 and CD40 work together in CD40/CD40L …

… : TEVs were modified with CD40 ligand (CD40L), which can target CD40 expressed on the
… were modified with CD40L for the effective induction of tumor-specific immune responses. It …

… The CD40/CD40L axis plays a central role in the generation of humoral immune responses
and is an attractive target for treating autoimmune diseases in the clinic. Here, we report the …

… The fundamental role of the CD40 receptor, a member … CD40L/CD154) in co-ordinating
immune responses has been widely recognised as an early event in initiating immune responses …