[HTML][HTML] Constitutive immune mechanisms: mediators of host defence and immune regulation
… or potentially disruptive immune responses. In addition, vigorous immune responses are not
… RNAi is another constitutive immune mechanism that directly controls viral replication. RNAi …
… RNAi is another constitutive immune mechanism that directly controls viral replication. RNAi …
[HTML][HTML] Gut microbiome and health: mechanistic insights
… and possibly immune diseases.23 Support for this and further new insight derived from …
have been found to affect the host immune response, providing an experimental system for …
have been found to affect the host immune response, providing an experimental system for …
[HTML][HTML] B cell depletion therapies in autoimmune disease: advances and mechanistic insights
DSW Lee, OL Rojas, JL Gommerman - Nature reviews Drug discovery, 2021 - nature.com
… Immune responses to antigens occur within secondary lymphoid organs (lymph nodes,
tonsils and spleen): the spleen supports immune responses to blood-borne antigens, whereas …
tonsils and spleen): the spleen supports immune responses to blood-borne antigens, whereas …
New insights into the immune functions of complement
ES Reis, DC Mastellos, G Hajishengallis… - Nature Reviews …, 2019 - nature.com
… mechanism during a T cell immune response 105 . It has been suggested that co-ligation
of MCP and CD35 on activated CD4 + T cells further potentiates the production of IL-10 by …
of MCP and CD35 on activated CD4 + T cells further potentiates the production of IL-10 by …
Toll‐like receptor polymorphism in host immune response to infectious diseases: A review
S Mukherjee, S Huda… - Scandinavian journal of …, 2019 - Wiley Online Library
… Population-based study dissecting the mechanistic insights of the effect of natural selection
upon human TLRs involving 158 individuals from different parts of the globe revealed that …
upon human TLRs involving 158 individuals from different parts of the globe revealed that …
[HTML][HTML] Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing
S Patel, S Srivastava, MR Singh, D Singh - Biomedicine & …, 2019 - Elsevier
… Although numerous studies are available that support delayed wound healing in diabetes
but detailed mechanistic insight including factors involved and their role still needs to be …
but detailed mechanistic insight including factors involved and their role still needs to be …
[HTML][HTML] Tumor microenvironment: a metabolic player that shapes the immune response
S Cassim, J Pouyssegur - International journal of molecular sciences, 2019 - mdpi.com
… insights on how tumor microenvironment metabolically instructs immune responsiveness. …
Mechanistically, tryptophan depletion activates general control nonderepressible 2 (GCN2), …
Mechanistically, tryptophan depletion activates general control nonderepressible 2 (GCN2), …
[HTML][HTML] Modulation of immune responses by particle size and shape
… and subsequent immune responses, particularly inflammasome activation and T cell activation.
Understanding how the physical properties of particles affect immune responses can aid …
Understanding how the physical properties of particles affect immune responses can aid …
Epigenetic regulation of the innate immune response to infection
Q Zhang, X Cao - Nature Reviews Immunology, 2019 - nature.com
… viral RNAs and preventing an excessive immune response and inflammatory damage 47 .
This mechanism may be used by viruses for immune evasion, contributing to chronic infection. …
This mechanism may be used by viruses for immune evasion, contributing to chronic infection. …
[HTML][HTML] Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2
… system in COVID-19, a deeper understanding of the mechanism behind the immune
dysregulation might give us clues for the clinical management of the severe cases and for …
dysregulation might give us clues for the clinical management of the severe cases and for …
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