Mechanisms of disease: inflammatory bowel diseases

GP Ramos, KA Papadakis - Mayo Clinic Proceedings, 2019 - Elsevier
… The intestinal mucosa in the normal bowel and in inflammatory bowel disease (IBD). On
exposure to environmental factors, patients with IBD have development of microbial dysbiosis …

The microbiome and inflammatory bowel disease

KL Glassner, BP Abraham, EMM Quigley - Journal of Allergy and Clinical …, 2020 - Elsevier
… The disease is thought to develop as a result of interactions between … in the development
of intestinal inflammation. Thus a germ-free environment prevents the development of colitis in …

Pathway paradigms revealed from the genetics of inflammatory bowel disease

DB Graham, RJ Xavier - Nature, 2020 - nature.com
Inflammatory bowel disease (IBD) is a complex genetic disease that is instigated and amplified
… This core set of pathways represents vulnerabilities to disease development that suggest …

[HTML][HTML] Influence of environmental factors in the development and outcomes of inflammatory bowel disease

A Vedamurthy, AN Ananthakrishnan - Gastroenterology & …, 2019 - ncbi.nlm.nih.gov
… Geographical variability and environmental risk factors in inflammatory bowel disease. Gut.
… of inflammatory bowel disease based on results from the Asia-Pacific Crohn’s and Colitis

The impact of inflammatory bowel disease in Canada 2018: epidemiology

GG Kaplan, CN Bernstein, S Coward… - Journal of the …, 2019 - academic.oup.com
Inflammatory bowel disease is more likely to develop in those who were exposed to antibiotics
within the … Infectious gastroenteritis and risk of developing inflammatory bowel disease. …

The four epidemiological stages in the global evolution of inflammatory bowel disease

GG Kaplan, JW Windsor - Nature reviews Gastroenterology & …, 2021 - nature.com
… The changing pattern in the incidence (orange) and prevalence (blue) of inflammatory bowel
disease (IBD) across the four the stages of IBD evolution. Developing countries are in the …

A comprehensive review and update on the pathogenesis of inflammatory bowel disease

Q Guan - Journal of immunology research, 2019 - Wiley Online Library
… Patients with inflammatory bowel disease (IBD) are at increased risk for developing colorectal
cancer. It is been found that MDSC accumulation is further increased in the lesions during …

Colorectal cancer in inflammatory bowel disease: mechanisms and management

SC Shah, SH Itzkowitz - Gastroenterology, 2022 - Elsevier
… Patients with inflammatory bowel disease (IBD) are at increased risk of developing
colorectal cancer (CRC), despite decreases in CRC incidence in recent years. Chronic …

Antibiotic use and the development of inflammatory bowel disease: a national case-control study in Sweden

LH Nguyen, AK Örtqvist, Y Cao, TG Simon… - The lancet …, 2020 - thelancet.com
Background Use of antibiotics in early life has been linked with childhood inflammatory bowel
disease (IBD), but data for adults are mixed, and based on smaller investigations that did …

History of inflammatory bowel diseases

GC Actis, R Pellicano, S Fagoonee… - Journal of clinical …, 2019 - mdpi.com
… with an increased risk of developing IBD were discovered, … incidence of IBD in developing
countries has been attributed … , physiological, and immunological development of the host. …