Inflammation and tumor progression: signaling pathways and targeted intervention

H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
… of inflammation, the crosstalk between tumor development and inflammatory processes.
We also highlight potential targets for harnessing inflammation in the treatment of cancer. …

An overview of Nrf2 signaling pathway and its role in inflammation

S Saha, B Buttari, E Panieri, E Profumo, L Saso - Molecules, 2020 - mdpi.com
… of Nrf2 signaling pathway in inflammation, therefore, it is also worthwhile to discuss natural
antioxidants which could modulate Nrf2-dependent treatment of inflammatory diseases [241]. …

[HTML][HTML] The anti-inflammatory and anti-oxidant mechanisms of the Keap1/Nrf2/ARE signaling pathway in chronic diseases

W Tu, H Wang, S Li, Q Liu, H Sha - Aging and disease, 2019 - ncbi.nlm.nih.gov
pathway and its anti-inflammatory and anti-oxidant effects, we hypothesize that the anti-inflammatory
/Nrf2/ARE signaling pathway. Hence, this would be the focus of our future research. …

Inflammation and atherosclerosis: signaling pathways and therapeutic intervention

P Kong, ZY Cui, XF Huang, DD Zhang… - Signal transduction and …, 2022 - nature.com
… inflammasome pathway and its regulated inflammatory cytokine … inflammatory signaling
pathways in atherosclerosis, and discuss the preclinical studies targeting these key pathways for …

Signaling pathways and targeted therapy for myocardial infarction

Q Zhang, L Wang, S Wang, H Cheng, L Xu… - Signal transduction and …, 2022 - nature.com
… These signaling pathways include the key players in inflammation … Since signaling pathways
play an important role in … at targeting these aberrant signaling pathways and improving the …

NF-κB signaling pathways in osteoarthritic cartilage destruction

MC Choi, J Jo, J Park, HK Kang, Y Park - Cells, 2019 - mdpi.com
… Because NF-κB acts as a general and essential inflammatory … to joint damage, synovial cells
stimulated by inflammatory … -dependent signaling pathways, further providing inflammatory

The JNK signaling pathway in inflammatory skin disorders and cancer

MB Hammouda, AE Ford, Y Liu, JY Zhang - Cells, 2020 - mdpi.com
… The JNK signaling pathway mediates a wide range of cellular processes, including cell …
-dependent JNK, Akt, and ERK signaling pathways, and consequently increases the expression …

PGE2 increases inflammatory damage in Escherichia coli-infected bovine endometrial tissue in vitro via the EP4-PKA signaling pathway

T Li, B Liu, H Guan, W Mao, L Wang… - Biology of …, 2019 - academic.oup.com
… associated with pathogen-induced inflammatory damage to the endometrium. To … inflammatory
damage, this study evaluated the production of PGE 2 , inflammatory factors, and damage-…

Dietary polyphenols suppress chronic inflammation by modulation of multiple inflammation-associated cell signaling pathways

I Jantan, MA Haque, L Arshad, H Harikrishnan… - The Journal of nutritional …, 2021 - Elsevier
… , intracellular cell signaling pathways play significant role. … signaling pathway in chronic
inflammatory diseases is essential as these networks are common to diverse inflammatory

The role of signaling pathways of inflammation and oxidative stress in development of senescence and aging phenotypes in cardiovascular disease

J Papaconstantinou - Cells, 2019 - mdpi.com
… response signaling pathways whose activities are elevated and stabilized in response to
age-associated endogenous and induced inflammation-… These inflammation-associated signal