Mitochondrial dysfunction, insulin resistance, and potential genetic implications: potential role of alterations in mitochondrial function in the pathogenesis of insulin …
P Sangwung, KF Petersen, GI Shulman… - …, 2020 - academic.oup.com
… to insulin action (insulin resistance [IR]) is coupled with an inadequate secretion of insulin
by … Insulin resistance has strong environmental influences, including reduced daily physical …
by … Insulin resistance has strong environmental influences, including reduced daily physical …
[HTML][HTML] Sphingolipids as a culprit of mitochondrial dysfunction in insulin resistance and type 2 diabetes
K Roszczyc-Owsiejczuk, P Zabielski - Frontiers in endocrinology, 2021 - frontiersin.org
… Indeed, Tubbs et al. demonstrated that a marked disruption of ER-mitochondria interactions
is an early stage preceding mitochondrial dysfunction and insulin resistance in the myotubes …
is an early stage preceding mitochondrial dysfunction and insulin resistance in the myotubes …
[HTML][HTML] Mitochondrial (dys) function and insulin resistance: from pathophysiological molecular mechanisms to the impact of diet
… Herein, we describe the mechanistic link between mitochondrial dysfunction and insulin
resistance in skeletal muscle alongside the intracellular pathways orchestrating …
resistance in skeletal muscle alongside the intracellular pathways orchestrating …
[HTML][HTML] Mitochondrial dysfunction in metabolic syndrome
P Prasun - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020 - Elsevier
… and systemic inflammation exacerbating insulin resistance [73]. In addition to adipocyte,
mitochondria dysfunction in skeletal muscles is significant contributor to insulin resistance [74,75…
mitochondria dysfunction in skeletal muscles is significant contributor to insulin resistance [74,75…
[HTML][HTML] Insulin resistance promotes Parkinson's disease through aberrant expression of α-synuclein, mitochondrial dysfunction, and deregulation of the polo-like …
CT Hong, KY Chen, W Wang, JY Chiu, D Wu, TY Chao… - Cells, 2020 - mdpi.com
… posit a novel link between mitochondrial dysfunction and aberration in SNCA expression …
to mitochondrial dysfunction, we observed that in the context of IR, impaired mitochondrial …
to mitochondrial dysfunction, we observed that in the context of IR, impaired mitochondrial …
[HTML][HTML] Nutri-stress, mitochondrial dysfunction, and insulin resistance—role of heat shock proteins
J Kuppuswami, GP Senthilkumar - Cell Stress and Chaperones, 2023 - Elsevier
… molecular events in causing insulin resistance and the nature of … insulin resistance. Ample
evidence suggests that the heat shock machinery regulates critical pathways in mitochondrial …
evidence suggests that the heat shock machinery regulates critical pathways in mitochondrial …
[HTML][HTML] Dexamethasone-induced mitochondrial dysfunction and insulin resistance-study in 3T3-L1 adipocytes and mitochondria isolated from mouse liver
G Luan, G Li, X Ma, Y Jin, N Hu, J Li, Z Wang, H Wang - Molecules, 2019 - mdpi.com
… , declined ATP synthesis, opening of the mitochondrial permeability transition pore (mPTP), …
that mitochondrial dysfunction occurs along with dexamethasone-induced insulin resistance …
that mitochondrial dysfunction occurs along with dexamethasone-induced insulin resistance …
Hyperandrogenism and insulin resistance induce gravid uterine defects in association with mitochondrial dysfunction and aberrant reactive oxygen species production
M Hu, Y Zhang, X Guo, W Jia, G Liu… - American Journal …, 2019 - journals.physiology.org
… expression of uterine VDAC, a mitochondrial outer membrane protein for controlling ROS …
that hyperandrogenism and insulin resistance trigger mitochondrial dysfunction and disrupt the …
that hyperandrogenism and insulin resistance trigger mitochondrial dysfunction and disrupt the …
Altered mitochondrial metabolism in the insulin‐resistant heart
M Makrecka‐Kuka, E Liepinsh, AJ Murray… - Acta …, 2020 - Wiley Online Library
… of the cause and effect of cardiac mitochondrial dysfunction in diabetes. Finally, we explore
how … interventions can prevent and treat metabolic and mitochondrial dysfunction in diabetes. …
how … interventions can prevent and treat metabolic and mitochondrial dysfunction in diabetes. …
[HTML][HTML] … by-products modulate adipogenesis-related inflammation, mitochondrial dysfunction, and insulin resistance in adipocytes, via insulin/PI3K/AKT signaling …
M Rebollo-Hernanz, Q Zhang, Y Aguilera… - Food and Chemical …, 2019 - Elsevier
… Suppressing macrophages-adipocytes interaction alleviated inflammation-triggered
mitochondrial dysfunction and insulin resistance. CSE and CHE are beneficial in reducing …
mitochondrial dysfunction and insulin resistance. CSE and CHE are beneficial in reducing …
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