[HTML][HTML] Iron in infection and immunity

M Nairz, G Weiss - Molecular Aspects of Medicine, 2020 - Elsevier
… , autoimmune disease or malignancy however, sequesters iron not only from infectious …
iron metabolism and immunity, focusing on host defense against relevant infections and on …

The battle for iron in enteric infections

A Sousa Gerós, A Simmons, H Drakesmith… - …, 2020 - Wiley Online Library
… inter-kingdom fight for iron is never-… iron homeostasis in the gastrointestinal tract. We first
detail how mammalian systemic and cellular iron homeostasis influences gastrointestinal iron

[HTML][HTML] Iron in immune cell function and host defense

D Haschka, A Hoffmann, G Weiss - Seminars in Cell & Developmental …, 2021 - Elsevier
… against microbial infections and help to limit bacterial multiplication, at least partly by binding
divalent metals like iron and deprive the pathogen of iron. Lipocalin 2 (Lcn2) can bind iron-…

Hepcidin, iron, and bacterial infection

JC Barton, RT Acton - Vitamins and hormones, 2019 - Elsevier
… reducing iron … , iron acquisition by bacteria, hepcidin actions in mice infected with selected
extracellular and intracellular bacteria, and reports of corresponding serious human infections. …

The impact of metal availability on immune function during infection

AJ Monteith, EP Skaar - Trends in Endocrinology & Metabolism, 2021 - cell.com
… During infection, invading bacterial pathogens must acquire essential metals, such as zinc,
manganese, iron… during infection. How the host manipulates nutrient metal availability during …

Iron in infectious diseases friend or foe?: The role of gut microbiota

ZŞ Aksoyalp, A Temel, BR Erdogan - … of Trace Elements in Medicine and …, 2023 - Elsevier
… Therefore, iron deficiency, iron supplementation, or iron targeted … to infections. We aimed
to discuss the relationship between iron, infection, and gut microbiota and evaluate the iron-…

[HTML][HTML] Microbial metabolite signaling is required for systemic iron homeostasis

NK Das, AJ Schwartz, G Barthel, N Inohara, Q Liu… - Cell metabolism, 2020 - cell.com
… an iron-dependent mechanism that inhibits host iron transport and storage. Using a high-throughput
screen of microbial … factor of intestinal iron absorption and increase the iron-storage …

[HTML][HTML] The role of iron homeostasis in remodeling immune function and regulating inflammatory disease

Q Mu, L Chen, X Gao, S Shen, W Sheng, J Min, F Wang - Science Bulletin, 2021 - Elsevier
… for their proliferation and for mediating their effector functions, in which iron … , iron homeostasis
and/or iron metabolism with respect to conferring protection against pathogen infection, …

The role of iron and siderophores in infection, and the development of siderophore antibiotics

MGP Page - Clinical Infectious Diseases, 2019 - academic.oup.com
… of iron to invading pathogens [7]. Tissue damage resulting from infection can alter local iron
homeostasis by enhancing iron-scavenging and macrophage sequestration of iron, heme, …

Dietary restriction of iron availability attenuates UPEC pathogenesis in a mouse model of urinary tract infection

KA Bauckman, R Matsuda… - American Journal …, 2019 - journals.physiology.org
… diet (LID) had significantly reduced UTI persistence than those fed a standard-ironiron diet
successfully reverses the severe infection and inflammation burden in a mouse model of iron