[HTML][HTML] Short-term exposure to air pollution (PM2.5) induces hypothalamic inflammation, and long-term leads to leptin resistance and obesity via Tlr4/Ikbke in mice

CM Campolim, L Weissmann, CKO Ferreira… - Scientific reports, 2020 - nature.com
… even worse, leading to leptin resistance, hyperphagia, and a … air pollution affects energy
homeostasis through the activation of hypothalamic inflammatory signaling and leptin resistance

Fine particulate matter air pollution and aortic perivascular adipose tissue: Oxidative stress, leptin, and vascular dysfunction

P Haberzettl, L Jin, DW Riggs, J Zhao… - Physiological …, 2021 - Wiley Online Library
… Exposure to fine particulate matter (PM 2.5 ) air pollution … PVAT following short-term air
pollution exposure. Mice were … and aorta, upregulated PVAT leptin mRNA expression without …

Air pollution accelerates the development of obesity and Alzheimer's disease: the role of leptin and inflammation-a mini-review

CM Campolim, BC Schimenes, MM Veras… - Frontiers in …, 2024 - frontiersin.org
… We examine evidence suggesting that immune system activation leads to leptin resistance,
a critical facet in these conditions. Additionally, we discuss the need for further research on …

[PDF][PDF] The impact of air pollution to obesity

S Simkova, M Veleminsky, RJ Sram - Neuroendocrinol. Lett., 2020 - nel.edu
… In this study air pollution by NOx exerted a stronger effect on BMI growth than traffic density.
… and ambient air pollution are associated with higher levels of cord blood leptin and HMW …

Maternal exposure to air pollution and umbilical asprosin concentration, a novel insulin-resistant marker

ZS Hosseini, H Heydari-Zarnagh, M Behmanesh… - Chemosphere, 2021 - Elsevier
… nearest major roads) and air pollution with umbilical asprosin … Our results suggested that
maternal exposure to air pollution … of the mechanisms whereby air pollutants impaired glucose …

[HTML][HTML] Duration-sensitive association between air pollution exposure and changes in cardiometabolic biomarkers: Evidence from a predominantly African American …

J Luo, MG Kibriya, F Jasmine, A Shaikh, Z Jin… - Environmental …, 2024 - Elsevier
Leptin regulates energy balance, and its level is generally proportional to body fat mass.
C-… , leptin, and C-peptide observed in this study suggests higher risks for insulin resistance, …

[HTML][HTML] Near-roadway air pollution, immune cells and adipokines among obese young adults

MM Rahman, FF Liu, SP Eckel… - Environmental …, 2022 - Springer
air pollution exposures with leptin; however, the association between NRAP and serum leptin
… increase both inhaled dose of air pollution and reduce leptin; therefore, observed effects of …

The mediating role of vascular inflammation in traffic-related air pollution associated changes in insulin resistance in healthy adults

H Xu, S Liu, Y Wang, R Wu, T Yi, T Wang, Y Zhu… - International Journal of …, 2022 - Elsevier
… Additionally, positive associations of HOMA-IR, adiponectin, and leptin with air pollutants
were found at prior 1–7 MA days, but inverse associations were found for resistin (Figs. 1 and 2)…

[HTML][HTML] Association between metabolic and hormonal derangements and professional exposure to urban pollution in a high intensity traffic area

A Molfino, MI Amabile, M Muscaritoli… - Frontiers in …, 2020 - frontiersin.org
… a cohort of policemen exposed to high levels of air pollution. … , in the non-exposed subjects,
only leptin serum levels were higher in … (insulin, ghrelin, and leptin), our data suggest that the …

Long-term exposure to air pollution raises circulating levels of proprotein convertase subtilisin/kexin type 9 in obese individuals

C Macchi, N Ferri, C Favero, L Cantone… - European Journal of …, 2019 - academic.oup.com
… In obese individuals, more sensitive to the damaging effects of environmental air pollution,
PM 10 exposure positively associates with proprotein convertase subtilisin/kexin type 9 …