Lipid metabolism in cancer: New perspectives and emerging mechanisms
LA Broadfield, AA Pane, A Talebi, JV Swinnen… - Developmental cell, 2021 - cell.com
… on cancer lipid metabolism has … lipid metabolism for anti-cancer therapies is attractive,
with recent work on small-molecule inhibitors identifying compounds to target lipid metabolism. …
with recent work on small-molecule inhibitors identifying compounds to target lipid metabolism. …
Lipid metabolism in cancer progression and therapeutic strategies
Y Fu, T Zou, X Shen, PJ Nelson, J Li, C Wu, J Yang… - MedComm, 2021 - Wiley Online Library
… Recent reports have highlighted the crucial role that FAs synthesis, uptake, and fatty acid
oxidation (FAO) play in cancer development and progression. Acetyl-coenzyme A (CoA), the …
oxidation (FAO) play in cancer development and progression. Acetyl-coenzyme A (CoA), the …
Alterations of lipid metabolism in cancer: implications in prognosis and treatment
LP Fernández, M Gomez de Cedron… - Frontiers in …, 2020 - frontiersin.org
… has emerged as essential for tumor development and … about the role of lipid metabolism
alterations in cancer. We will … of lipid metabolism biomarkers in the most frequent types of …
alterations in cancer. We will … of lipid metabolism biomarkers in the most frequent types of …
Adipocyte and lipid metabolism in cancer drug resistance
Y Cao - The Journal of clinical investigation, 2019 - Am Soc Clin Investig
… of adipocytes and cancer lipid metabolism on cancer drug responses and … development
of new therapeutics targeting lipid metabolism would offer exciting opportunities for cancer …
of new therapeutics targeting lipid metabolism would offer exciting opportunities for cancer …
The role of lipid metabolism in gastric cancer
MY Cui, X Yi, DX Zhu, J Wu - Frontiers in Oncology, 2022 - frontiersin.org
… Plasma oxidized low-density lipoprotein (oxLDL) is considered a risk factor for tumor
development in patients with abnormal lipid metabolism. LDL binds to LDL, transporting cholesterol …
development in patients with abnormal lipid metabolism. LDL binds to LDL, transporting cholesterol …
Lipid metabolism in cancer cells under metabolic stress
… The development and progression of cancer is typically accompanied by marked changes …
challenging conditions, cancer cells adapt their metabolism, including that of lipids. One of the …
challenging conditions, cancer cells adapt their metabolism, including that of lipids. One of the …
Aberrant lipid metabolism as a therapeutic target in liver cancer
ED Pope III, EO Kimbrough, LP Vemireddy… - Expert opinion on …, 2019 - Taylor & Francis
… pathways in cancer cell survival. Lipid metabolism has a role in HCC development; aberrant
… Areas covered: We discuss aberrant lipid metabolism and the promise of multiple targets, in …
… Areas covered: We discuss aberrant lipid metabolism and the promise of multiple targets, in …
[PDF][PDF] The heterogeneity of lipid metabolism in cancer
… Therapeutic strategies targeting lipid metabolism are now in various stages of clinical
development, and one approach worth highlighting is the “repurposing” of drugs from cardiology […
development, and one approach worth highlighting is the “repurposing” of drugs from cardiology […
The Role of Lipid Metabolism Disorders in the Development of Thyroid Cancer
M Lukasiewicz, A Zwara, J Kowalski, A Mika… - International Journal of …, 2024 - mdpi.com
… In this review, we examine lipid metabolism at different stages, … development. Recent
scientific efforts have revealed disturbances in lipid homeostasis that are specific to thyroid cancer, …
scientific efforts have revealed disturbances in lipid homeostasis that are specific to thyroid cancer, …
Upregulation of lipid metabolism genes in the breast prior to cancer diagnosis
… We further show that the breast tissue susceptible to cancer development has an enrichment
in lipid metabolism-related genes not only in the epithelial compartment but also in the …
in lipid metabolism-related genes not only in the epithelial compartment but also in the …
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