Lipid metabolism in cancer: New perspectives and emerging mechanisms

LA Broadfield, AA Pane, A Talebi, JV Swinnen… - Developmental cell, 2021 - cell.com
… on cancer lipid metabolism has … lipid metabolism for anti-cancer therapies is attractive,
with recent work on small-molecule inhibitors identifying compounds to target lipid metabolism. …

Lipid metabolism in cancer progression and therapeutic strategies

Y Fu, T Zou, X Shen, PJ Nelson, J Li, C Wu, J Yang… - MedComm, 2021 - Wiley Online Library
… Recent reports have highlighted the crucial role that FAs synthesis, uptake, and fatty acid
oxidation (FAO) play in cancer development and progression. Acetyl-coenzyme A (CoA), the …

Alterations of lipid metabolism in cancer: implications in prognosis and treatment

LP Fernández, M Gomez de Cedron… - Frontiers in …, 2020 - frontiersin.org
… has emerged as essential for tumor development and … about the role of lipid metabolism
alterations in cancer. We will … of lipid metabolism biomarkers in the most frequent types of …

Adipocyte and lipid metabolism in cancer drug resistance

Y Cao - The Journal of clinical investigation, 2019 - Am Soc Clin Investig
… of adipocytes and cancer lipid metabolism on cancer drug responses and … development
of new therapeutics targeting lipid metabolism would offer exciting opportunities for cancer

The role of lipid metabolism in gastric cancer

MY Cui, X Yi, DX Zhu, J Wu - Frontiers in Oncology, 2022 - frontiersin.org
… Plasma oxidized low-density lipoprotein (oxLDL) is considered a risk factor for tumor
development in patients with abnormal lipid metabolism. LDL binds to LDL, transporting cholesterol …

Lipid metabolism in cancer cells under metabolic stress

R Munir, J Lisec, JV Swinnen, N Zaidi - British journal of cancer, 2019 - nature.com
… The development and progression of cancer is typically accompanied by marked changes …
challenging conditions, cancer cells adapt their metabolism, including that of lipids. One of the …

Aberrant lipid metabolism as a therapeutic target in liver cancer

ED Pope III, EO Kimbrough, LP Vemireddy… - Expert opinion on …, 2019 - Taylor & Francis
… pathways in cancer cell survival. Lipid metabolism has a role in HCC development; aberrant
… Areas covered: We discuss aberrant lipid metabolism and the promise of multiple targets, in …

[PDF][PDF] The heterogeneity of lipid metabolism in cancer

JK Park, NJ Coffey, A Limoges, A Le - … of cancer metabolism, 2021 - library.oapen.org
… Therapeutic strategies targeting lipid metabolism are now in various stages of clinical
development, and one approach worth highlighting is the “repurposing” of drugs from cardiology […

The Role of Lipid Metabolism Disorders in the Development of Thyroid Cancer

M Lukasiewicz, A Zwara, J Kowalski, A Mika… - International Journal of …, 2024 - mdpi.com
… In this review, we examine lipid metabolism at different stages, … development. Recent
scientific efforts have revealed disturbances in lipid homeostasis that are specific to thyroid cancer, …

Upregulation of lipid metabolism genes in the breast prior to cancer diagnosis

N Marino, R German, X Rao, E Simpson, S Liu… - … Breast Cancer, 2020 - nature.com
… We further show that the breast tissue susceptible to cancer development has an enrichment
in lipid metabolism-related genes not only in the epithelial compartment but also in the …