[HTML][HTML] Association of inflammatory cytokines with non-alcoholic fatty liver disease

Y Duan, X Pan, J Luo, X Xiao, J Li… - Frontiers in …, 2022 - frontiersin.org
… have shown that TNF-α can be used as a predictor for the development of NAFLD (56, 82). …
81, 82), the results of the meta-analysis showed that TNF-α can increase the risk of NAFLD. …

[HTML][HTML] Multiple parallel hits hypothesis in nonalcoholic fatty liver disease: revisited after a decade

H Tilg, TE Adolph, AR Moschen - Hepatology, 2021 - journals.lww.com
fatty liver disease (NAFLD) is an epidemic liver disease, affecting approximately one quarter
of the entire population in the world. ( 1 ) This disease … advanced fibrosis, liver cirrhosis, and …

[HTML][HTML] Obesity, nonalcoholic fatty liver disease and adipocytokines network in promotion of cancer

R Divella, A Mazzocca, A Daniele… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
… the incidence of nonalcoholic fatty liver disease (NAFLD) is increasing and becoming one
of the most common causes of liver disease worldwide. Also, NAFLD is considered one the …

[HTML][HTML] TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice

…, A Vogel, K John, MP Manns, A Teufel… - … death & disease, 2020 - nature.com
… Non-alcoholic fatty liver disease (NAFLD) represents one of the most common causes of
chronic liver diseases, ranging from simple steatosis (non-alcoholic fatty liver; NAFL) to non-…

[HTML][HTML] TNF in the liver: targeting a central player in inflammation

G Tiegs, AK Horst - Seminars in immunopathology, 2022 - Springer
… role of TNF for induction of liver cell death prompted many investigators to study the role of
TNF and its receptors in liver disease, liver … of major TNF effects in Table 1). The term sterile …

[HTML][HTML] A novel TNF-α-targeting aptamer for TNF-α-mediated acute lung injury and acute liver failure

WY Lai, JW Wang, BT Huang, EPY Lin, PC Yang - Theranostics, 2019 - ncbi.nlm.nih.gov
… with aptTNF-α/aptTNF-α-PEG not only rescued acute liver damage but also … -α/aptTNF-α-PEG
in ALF. Taken together, we showed that aptTNF-α/aptTNF-α-PEG possessed good liver

[HTML][HTML] Immunological mechanisms and therapeutic targets of fatty liver diseases

H Wang, W Mehal, LE Nagy, Y Rotman - Cellular & Molecular …, 2021 - nature.com
… factors in the pathogeneses of chronic liver diseases worldwide, causing alcoholic liver
disease (ALD) and nonalcoholic fatty liver disease (NAFLD), respectively. Although there are …

Tumor Necrosis Factor α–Induced Protein 8–Like 2 Alleviates Nonalcoholic Fatty Liver Disease Through Suppressing Transforming Growth Factor Beta–Activated …

Y Liu, J Song, J Yang, J Zheng, L Yang, J Gao… - …, 2021 - Wiley Online Library
Tumor necrosis factor α– induced protein 8– like 2 (TIPE2) plays a protective role in a cluster
of liver diseases, such as autoimmune hepatitis, … However, the function of TIPE2 in NAFLD

Ghrelin Reduces TNF-αInduced Human Hepatocyte Apoptosis, Autophagy, and Pyroptosis: Role in Obesity-Associated NAFLD

…, I Colina, MM Malagón, A Rodríguez - The Journal of …, 2019 - academic.oup.com
… and NAFLD might constitute a compensatory mechanism to overcome TNF-α–induced
hepatocyte apoptosis, autophagy, and pyroptosis. Nonalcoholic fatty liver disease (NAFLD) …

[HTML][HTML] The role of tumor necrosis factor alpha (TNF-α) in autoimmune disease and current TNF-α inhibitors in therapeutics

D Jang, AH Lee, HY Shin, HR Song, JH Park… - International journal of …, 2021 - mdpi.com
… The impact of TNF-α signaling on each type of autoimmune disease will be introduced in …
of current TNF-α inhibitors utilized as therapeutic drugs against autoimmune diseases. …