The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

K Kazankov, SMD Jørgensen, KL Thomsen… - Nature reviews …, 2019 - nature.com
… roles in liver immune homeostasis and the development of other liver diseases that share
important endpoints with NAFLD, such as chronic viral hepatitis and alcoholic liver disease 13 …

[HTML][HTML] Noncanonical NF-κB signaling pathway in liver diseases

Q Chen, X Lu, X Zhang - Journal of clinical and translational …, 2021 - ncbi.nlm.nih.gov
… of various liver diseases, including metabolic liver disease, autoimmune liver disease, and
viral … NF-κB signaling molecules in various liver diseases. In particular, we also discuss the …

Environmental perfluoroalkyl acid exposures are associated with liver disease characterized by apoptosis and altered serum adipocytokines

J Bassler, A Ducatman, M Elliott, S Wen… - Environmental …, 2019 - Elsevier
Tumor necrosis factor α and … liver disease may be asymptomatic and subclinical early in its
course, the present study applies mechanistic serologic biomarkers to further investigate liver

Effects of curcumol on liver function and fibrosis in rats of nonalcoholic fatty liver disease and its mechanism

SY Qi, H Huang, YK Li, LG Pei… - … Ying Yong Sheng li xue za …, 2021 - europepmc.org
… The percentage of liver to body weight, and the levels of high density lipoprotein (HDL), …
The liver fibrosis was observed by HE staining. The expressions of α-smooth muscle actin (α-…

[HTML][HTML] Pyroptosis in liver disease: new insights into disease mechanisms

J Wu, S Lin, B Wan, B Velani, Y Zhu - Aging and disease, 2019 - ncbi.nlm.nih.gov
… some diseases, such as acute or chronic hepatitis and liver … of cell death in different liver
diseases will be evaluated in this … non-alcoholic fatty liver disease, as well as in liver failure. …

Serpina3c deficiency induced necroptosis promotes non‐alcoholic fatty liver disease through β‐catenin/Foxo1/TLR4 signaling

LL Qian, JJ Ji, Y Jiang, JQ Guo, Y Wu… - The FASEB …, 2022 - Wiley Online Library
fatty liver disease (NAFLD) is a public health challenge and an increasing cause of
chronic liver disease … the precise role of serpina3c in the process of NAFLD. Male Apoe−/−/serpina3c−…

[HTML][HTML] Inflammatory markers response to citrulline supplementation in patients with non-alcoholic fatty liver disease: A randomized, double blind, placebo-controlled …

…, M Hedayati, A Faghihi, S Agah, A Hekmatdoost - BMC research …, 2019 - Springer
… Some studies have shown potential effects of Cit on reducing inflammatory markers such
as tumor necrosis factor α (TNF-α) and interleukin-6 (IL-6) [12, 15, 16], which can prevent …

[HTML][HTML] Inflammation and liver cancer: molecular mechanisms and therapeutic targets

YM Yang, SY Kim, E Seki - Seminars in liver disease, 2019 - thieme-connect.com
… and nonalcoholic fatty liver diseases. The inflammatory cytokines tumor necrosis factor-α
and … The authors will also discuss cholangiocarcinoma and liver metastasis because biliary …

[HTML][HTML] Pathogenesis, early diagnosis, and therapeutic management of alcoholic liver disease

LZ Kong, N Chandimali, YH Han, DH Lee… - International journal of …, 2019 - mdpi.com
liver disease (ALD) refers to the damages to the liver and its functions due to alcohol
overconsumption. It consists of fatty liver/… , chronic hepatitis with liver fibrosis or cirrhosis, and …

IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease

…, IH Mckillop, O Quehenberger, E Dennis, A Saltiel… - Journal of …, 2020 - Elsevier
… injury, such as HBV/HCV infections, and metabolic diseases, including non-alcoholic
steatohepatitis (NASH) and alcoholic liver disease (ALD). With the introduction of new therapies, …