Fatigue in chronic liver disease: New insights and therapeutic approaches

MG Swain, DEJ Jones - Liver International, 2019 - Wiley Online Library
… in patients with chronic liver disease remains incomplete. A … Currently, the management
of fatigue in chronic liver disease … of fatigue in chronic liver disease. However, evidence and …

[HTML][HTML] Macrophages in obesity and non-alcoholic fatty liver disease: Crosstalk with metabolism

S Lefere, F Tacke - JHEP reports, 2019 - Elsevier
… of fatty liver disease, highlighting putative macrophage-mediated mechanisms that link NAFLD
and cardiovascular disease, … of macrophages as therapeutic targets in fatty liver disease. …

[HTML][HTML] Kupffer cells: inflammation pathways and cell-cell interactions in alcohol-associated liver disease

E Slevin, L Baiocchi, N Wu, B Ekser, K Sato… - The American Journal of …, 2020 - Elsevier
… patients with this disease. Alcohol-associated liver disease (ALD) is a major cause of chronic
liver injury, … This ranges from the accumulation of lipids in the liver (steatosis), steatosis with …

Osteopontin takes center stage in chronic liver disease

Z Song, W Chen, D Athavale, X Ge, R Desert… - …, 2021 - Wiley Online Library
liver disease and non- alcoholic fatty liver disease. We describe the mechanisms
whereby OPN participates in inflammation and liverliver disease. (Hepatology 2021;73:1594-1608). …

The role of gut-derived lipopolysaccharides and the intestinal barrier in fatty liver diseases

L An, U Wirth, D Koch, M Schirren, M Drefs… - Journal of …, 2022 - Elsevier
… both contribute to chronic liver disease by abnormal regulation of the gut-liver axis. Thereby,
… of liver tissue. The review further underlines that endotoxemia is observed in both NAFLD

[HTML][HTML] Immunomodulatory role of the extracellular matrix within the liver disease microenvironment

CE McQuitty, R Williams, S Chokshi… - Frontiers in …, 2020 - frontiersin.org
liver ECM and diseased liver ECM from different aetiologies. However, currently available
proteomics data on human liver … in different liver diseases and during disease progression and …

[HTML][HTML] Integrative evidence construction for resveratrol treatment of nonalcoholic fatty liver disease: preclinical and clinical meta-analyses

X He, Y Li, X Deng, X Xiao, J Zeng - Frontiers in Pharmacology, 2023 - frontiersin.org
… Additionally, resveratrol alleviated nonalcoholic fatty liver disease primarily via AMPK/… fatty
liver disease, but demonstrated the liver-protective effects on nonalcoholic fatty liver disease. …

[HTML][HTML] Understanding the cellular interactome of non-alcoholic fatty liver disease

SJ Wallace, F Tacke, RF Schwabe, NC Henderson - JHEP Reports, 2022 - Elsevier
liver disease (CLD) and mortality from end-stage liver failure … patients with non-alcoholic fatty
liver disease (NAFLD), with an … NAFLD associated with inflammation, fibrosis and increased …

[HTML][HTML] Role of necroptosis in chronic hepatic inflammation and fibrosis in a mouse model of increased oxidative stress

…, R Selvarani, GH Royce, M Kinter, A Richardson… - Free Radical Biology …, 2021 - Elsevier
… mice progresses from non-alcoholic fatty liver disease (NAFLD) to non-alcoholic … in NAFLD
to NASH progression, and liver inflammation is the main mechanism that drives the disease

Intestinal barrier function–non-alcoholic fatty liver disease interactions and possible role of gut microbiota

Y Cui, Q Wang, R Chang, X Zhou… - Journal of agricultural and …, 2019 - ACS Publications
… levels of tumor necrosis factor α (TNF-α), alanine aminotransferase (ALT), and serum
aspartate aminotransferase (AST). (18) In addition, the prevalence of SIBO and TNF-α was higher …