[HTML][HTML] Recent advances on the role of EGFR tyrosine kinase inhibitors in the management of NSCLC with uncommon, non exon 20 insertions, EGFR mutations

A Passaro, T Mok, S Peters, S Popat, MJ Ahn… - Journal of Thoracic …, 2021 - Elsevier
EGFR mutations. Moving forward, it will be important to include uncommon EGFR mutations
in the first-line molecular analysis of all patients with adenocarcinoma of the lung, as this …

Sequential afatinib and osimertinib in patients with EGFR mutation-positive non-small-cell lung cancer: updated analysis of the observational GioTag study

MJ Hochmair, A Morabito, D Hao, CT Yang… - Future …, 2019 - Taylor & Francis
… Several EGFR tyrosine kinase inhibitors (TKIs) are now available for the treatment of EGFR
mutation-positive non-small-cell lung cancer (NSCLC): the first-generation, reversible EGFR

Lazertinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: results from the dose escalation and dose expansion parts of a first-in-human …

MJ Ahn, JY Han, KH Lee, SW Kim, DW Kim… - The Lancet …, 2019 - thelancet.com
… to inhibit not only the standard sensitising EGFR mutations occurring in non-small-cell lung
cancer (NSCLC), but also T790M, an exon 20 point mutation, which commonly emerges as a …

Identifying relationships between imaging phenotypes and lung cancer-related mutation status: EGFR and KRAS

G Pinheiro, T Pereira, C Dias, C Freitas, V Hespanhol… - Scientific reports, 2020 - nature.com
… with cancer treatment 15 . Several clinical trials have been performed to evaluate the
efficacy and safety of treatments for lung cancer patients with EGFR mutations 16 . EGFR is a …

[HTML][HTML] Impact of feature harmonization on radiogenomics analysis: Prediction of EGFR and KRAS mutations from non-small cell lung cancer PET/CT images

I Shiri, M Amini, M Nazari, G Hajianfar, AH Avval… - Computers in biology …, 2022 - Elsevier
… had generally a better impact on features for EGFR compared to KRAS status prediction, its
… successful prediction of EGFR and KRAS mutation statuses in lung cancer patients. Thus, by …

The advance of the third‑generation EGFR‑TKI in the treatment of non‑small cell lung cancer

Z Cheng, H Cui, Y Wang, J Yang, C Lin… - Oncology …, 2023 - spandidos-publications.com
… Therefore, for patients with EGFR mutation positivity in advanced lung cancer, osimertinib
has established its unshakable position in the targeted treatment of NSCLC due to its …

[HTML][HTML] ESMO expert consensus statements on the management of EGFR mutant non-small-cell lung cancer

A Passaro, N Leighl, F Blackhall, S Popat, K Kerr… - Annals of …, 2022 - Elsevier
… The most common type of activating EGFR mutation is the in-frame deletion of … lung cancer
in patients with EGFR or ALK-wildtype NSCLC. Clinical trials evidence suggests that EGFR- …

Randomized Phase III Study of Gefitinib Versus Cisplatin Plus Vinorelbine for Patients With Resected Stage II-IIIA Non–Small-Cell Lung Cancer With EGFR Mutation  …

H Tada, T Mitsudomi, T Misumi, K Sugio… - Journal of Clinical …, 2022 - ascopubs.org
… to EGFR mutations conducted before EGFR mutations were … subset of patients with EGFR
mutation treated with erlotinib. … with lung cancer selected with respect to EGFR mutation

Cardiac Adverse Events in EGFR-Mutated Non-Small Cell Lung Cancer Treated With Osimertinib

K Kunimasa, R Kamada, T Oka, M Oboshi, M Kimura… - Cardio Oncology, 2020 - jacc.org
… non–small cell lung cancer (NSCLC) with confirmed EGFR mutations who received
osimertinib monotherapy from 2014 to 2019 at the Osaka International Cancer Institute (Osaka, …

[HTML][HTML] EGFR mutation tracking predicts survival in advanced EGFR-mutated non-small cell lung cancer patients treated with osimertinib

A Buder, MJ Hochmair, U Setinek… - … Lung Cancer …, 2020 - ncbi.nlm.nih.gov
… (EGFR)-mutated non-small cell lung cancer (NSCLC) patients and T790M-mediated resistance.
We investigated the clinical utility of EGFR mutation … in metastatic, EGFR-mutant NSCLC …