… lung disease associated with progressive decline of lung function is the main source of
morbidity and mortality in cystic fibrosis (… of neutrophil activity in the reduction of lung function [2]. …

… Subsequently, we stratified patients into lung disease categories of increasing disease
severity to further investigate relationships between microbiota characteristics and …

… lung disease or await lung transplantation. While the hope is that these drug compounds will
prevent lung … need to care for people with advanced lung disease. The focus of this review …

… increased antimicrobial resistance and accelerate lung disease. Although the pathogenicity
of … be associated with worsened clinical outcomes including more severe lung disease.[13] …

… Chronic airway infection is the hallmark of CF lung disease. Bacterial colonization of the
respiratory tract occurs within the first few days of life in CF infants. The most common organisms …

… Cystic fibrosis (CF) is a common autosomal recessive disease caused by mutations in the
cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes an anion …

… of patients with cystic fibrosis. Reproduced with permission of the ERS © 2019. Elborn57 …
It took several decades to find ways to combat lung disease by clearing the airways using …

… Cystic fibrosis (CF) is an autosomal recessive disorder which results from mutations in the
cystic fibrosis transmembrane regulator (CFTR) gene encoding the CFTR protein. Defects in …

… With the widespread introduction of newborn screening for cystic fibrosis (CF), there has
been considerable emphasis on the need to develop objective markers of lung health that can …

… on lung disease in young children with cystic fibrosis is … with cystic fibrosis is being recognised
more frequently and is associated with some early structural changes in CF lung disease …