Magnetic resonance imaging detects progression of lung disease and impact of newborn screening in preschool children with cystic fibrosis

M Stahl, E Steinke, SY Graeber, C Joachim… - American journal of …, 2021 - atsjournals.org
… detect early lung disease in infants and preschool children with cystic fibrosis (CF) without
radiation exposure. However, the ability of MRI to detect the progression of lung disease and …

Oral non‐steroidal anti‐inflammatory drug therapy for lung disease in cystic fibrosis

LC Lands, S Stanojevic - Cochrane Database of Systematic …, 2019 - cochranelibrary.com
… The results of this review suggest that high‐dose ibuprofen probably slows the progression
of lung disease in children with cystic fibrosis (CF). There may also be a beneficial effect on …

Cystic fibrosis: a review

T Ong, BW Ramsey - Jama, 2023 - jamanetwork.com
… The effect of azithromycin on structural lung disease in infants with cystic fibrosis (COMBAT
CF): a phase 3, randomised, double-blind, placebo-controlled clinical trial.  …

Cell therapy for cystic fibrosis lung disease: regenerative basal cell amplification

D Hayes Jr, BT Kopp, CL Hill, SW Lallier… - Stem cells …, 2019 - academic.oup.com
… Our long-term goal is to develop a cell therapy for cystic fibrosis (CF) lung disease. CF is …
The concept underlying our cell therapy initiative is that CF lung disease can be reversed …

IL-17A from innate and adaptive lymphocytes contributes to inflammation and damage in cystic fibrosis lung disease

M Hagner, M Albrecht, M Guerra… - European …, 2021 - Eur Respiratory Soc
cystic fibrosis (CF), but its cellular sources and role in the pathogenesis of CF lung disease
… determine the sources of IL-17A and its role in airway inflammation and lung damage in CF. …

[HTML][HTML] Treatment of pulmonary disease of cystic fibrosis: A comprehensive review

RM Girón Moreno, M García-Clemente… - Antibiotics, 2021 - mdpi.com
… Treatment of inflammatory lung diseases with macrolides began with the use of erythromycin
in patients with diffuse panbronchiolitis, in which it was observed that those who were …

Viral vectors, animal models, and cellular targets for gene therapy of cystic fibrosis lung disease

Y Tang, Z Yan, JF Engelhardt - Human gene therapy, 2020 - liebertpub.com
… ) to treat cystic fibrosis (CF) lung disease, … lung pathogenesis and the cellular targets for
gene therapy, and the development of new animal models that reproduce the human CF disease

Pulmonary complications of cystic fibrosis

B Garcia, PA Flume - Seminars in respiratory and critical care …, 2019 - thieme-connect.com
Cystic fibrosis (CF) lung disease is characterized by the development of progressive
bronchiectasis and impaired lung … The mechanism by which CF lung disease develops is the …

[HTML][HTML] Update in cystic fibrosis 2018

BW Ramsey, GP Downey, CH Goss - American Journal of …, 2019 - atsjournals.org
… with both lung disease progression and lung function preservation, … of CF lung disease (67).
Although genetic factors impact … lung disease in infants and preschool children with cystic

[HTML][HTML] The relationship between lung disease severity and the sputum proteome in cystic fibrosis

RE Maher, E Barrett, RJ Beynon, VM Harman… - Respiratory …, 2022 - Elsevier
bronchiectasis seen in cystic fibrosis (CF) lung disease leads to progressive respiratory failure
and premature death [1]. Dysfunction of the cystic fibrosis … CF lung disease could aid the …