… cystic fibrosis transmembrane conductance regulator (CFTR) triple combination therapy used
for the treatment of cystic fibrosis … in cystic fibrosis adults with mild to moderate lung disease…

… In addition, we describe animal models used to study human cystic fibrosis disease and …
lung disease is the main cause of CF complications and patient mortality. The course of disease …

… that gains in lung function occur more slowly in our population with advanced lung disease,
and longer follow up may reveal a more substantial response (6). Most of the lung function …

… Moreover, the critical pathogen in chronic lung disease is an unusual morphotype of P. …
Progressive lung disease remains the leading cause of morbidity and mortality in these …

… and the progression of lung disease do not fully explain the lung phenotypes of CF patients.
For … Until recently, CF-related lung disease research focused on major pathogens such as P. …

… with cystic fibrosis (CF), progressive lung disease … lung disease relies primarily on spirometry
to measure lung function which is relatively insensitive in individuals with mild lung disease…

… The current study reinforces the role of LTx in the treatment of end-stage lung disease
secondary to CF. Clearly, outcomes have continued to improve, and the 50% 5-year survival rule …

… -related lung disease to be effective, the onset and progression of the lung disease should
be … either indirectly by monitoring lung function or more directly by monitoring lung structure. …

… Conventional pulmonary function tests appear normal in early cystic fibrosis (CF) lung
disease. Therefore, new diagnostic approaches are required that can detect CF lung disease in …

… For individuals with progressive advanced CF lung disease (ACFLD), lung transplantation
… , and their impact on lung disease progression and the need for lung transplantation as the …