… efficacy against controlled human malaria infections (CHMI) and against naturally acquired
infections. Expert Opinion: Effective vaccination … disappointing efficacy of malaria vaccine …

… malaria vaccine and was shown to have modest efficacy … malaria vaccine that is able to
induce long-lasting protective … factors including the complexity of the malaria parasite’s life-cycle, …

… reducing the global malaria burden (1). … malaria vaccines with >75% efficacy against
clinical malaria and suitable for use in all malaria-endemic areas by 2030 (duration of protection …

… Vaccines using a single allele may have lower efficacy … the efficacy of the CSP-based RTS,S
malaria vaccine may be … falciparum CSP alleles that diverge from the 3D7 vaccine allele, …

… The protective efficacy of the combination as compared with the vaccine alone against these
outcomes was 59.6% (95% CI, 54.7 to 64.0), 70.6% (95% CI, 42.3 to 85.0), and 75.3% (95% …

… Protective efficacy of PEV was first demonstrated in a human in the 1970s using radiation-attenuated
WSV delivered through hundreds of mosquito bites; the vaccinee was protected …

… that prioritizes malaria vaccine … vaccines might improve upon the protective efficacy of RTS,S
or R21 for children, or address the wider malaria scourge by preventing pregnancy malaria, …

… The RTS,S/AS01 malaria vaccine provides moderate efficacy and is … malaria vaccines,
including novel approaches that build on principles learned from RTS,S development, vaccination …

… , and the estimated protective efficacy was 29% by proportional analysis (11). A recent trial
of this attenuated sporozoite vaccine in Kenya failed to demonstrate significant efficacy in 5- …

… most advanced malaria vaccine candidate with a mean efficacy of ~… malaria vaccine among
children in sub-Saharan Africa and other regions with moderate to high P. falciparum malaria …