… with existing drugs, or perhaps during the development of a new drug, when it is necessary
to know where metabolism occurs in order to anticipate future drug– drug interactions, for …

… TH have been implicated in multiple processes related to brain formation in mammals—…
developing mammalian brain. We also discuss their potential role in vertebrate brain evolution …

… Sox11 is mainly expressed in neurogenic niches of the adult mammalian brain and its ectopic
expression promotes neuronal differentiation of NPCs [86]. In addition, in vivo conditional …

… -eating birds and other mammals is the methylation of the Hg 2+ to MeHg in the aquatic
environment. MeHg is an important product of microbial metabolism and can be an intermediate …

… Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain
… INMT and AADC mRNA in rat brain and periphery, and brain concentrations of DMT in rats. …

… drug therapy, but in vivo studies on direct chemical reprogramming and efficient drug delivery
across blood–brain-… Nevertheless, it is worth the great effort to develop such drug therapy …

… drugs … mammalian brain that have profound implications for our understanding of the
neuropharmacology of cannabinoid-based drugs and their effects on mental health and the brain. A …

… drug-metabolizing enzymes within the brain endothelial cells, such as CYP 450 enzymes
(CYP1B1 and CYP2U1, CYP-3AF), results in the formation of the metabolic … mammalian brain …

… has generated a detailed multilevel genome-wide view on the protein-coding genes of the
mammalian brain, where we compared tissue specificity across the whole body, as classified …

… KATII is the most prevalent KAT in the mammalian brain and is being pursued as a drug
target for schizophrenia and cognitive impairment disorders. As KATII was recently shown to …