[HTML][HTML] MAPK/ERK signaling in regulation of renal differentiation

K Kurtzeborn, HN Kwon, S Kuure - International Journal of Molecular …, 2019 - mdpi.com
… of how mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) …
/ERK functions at the cellular level, and specifically during renal development, are only …

Autophagy activates EGR1 via MAPK/ERK to induce FGF2 in renal tubular cells for fibroblast activation and fibrosis during maladaptive kidney repair

MJ Livingston, M Zhang, SH Kwon, JK Chen, H Li… - Autophagy, 2024 - Taylor & Francis
… of renal fibroblasts to promote fibrosis. Upstream of EGR1, autophagy activated MAPK1/ERK2
(mitogen-activated protein kinase 1)-MAPK3/ERK1 in renal … the development of renal

A comprehensive map of mRNAs and their isoforms across all 14 renal tubule segments of mouse

L Chen, CL Chou, MA Knepper - Journal of the American Society …, 2021 - journals.lww.com
… TSA Plus fluorophores at the concentration of 1:1500 were used to develop signals. Once
the signals were developed for each channel, a standard immunohistochemistry protocol was …

Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways

X Geng, A Ma, J He, L Wang, Y Jia, G Shao… - Acta Pharmacologica …, 2020 - nature.com
… GTs exerts a fascinating inhibitory effect on renal cyst development in an ADPKD mouse
model via downregulating Ras/mitogen-activated protein kinase (MAPK) signaling and …

[HTML][HTML] Cellular and molecular mechanisms of kidney development: from the embryo to the kidney organoid

N Khoshdel Rad, N Aghdami… - Frontiers in cell and …, 2020 - frontiersin.org
… During renal development, Lim1 is expressed in … , mitogen activated protein kinase; NRP1,
neuropilin 1; P, phosphate group; PI3K, phosphatidylinositol 3-kinase; PKC, protein kinase C; …

[HTML][HTML] MAP4K family kinases and DUSP family phosphatases in T-cell signaling and systemic lupus erythematosus

HC Chuang, TH Tan - Cells, 2019 - mdpi.com
development of early diagnostic biomarkers and therapeutic targets for SLE is desirable.
Mitogen-activated protein kinase kinase kinase kinases (… with the poor renal outcome of lupus …

[PDF][PDF] Mouse kidney development

AJ Davidson - African Scientist, 2019 - publications.africanscientistjournal …
… genetic hierarchies governing renal development will provide … renal lineages in vitro, and
further our understanding of renal … Erk MAP kinase regulates branching morphogenesis in the …

[HTML][HTML] Signaling pathways involved in diabetic renal fibrosis

Y Zhang, D Jin, X Kang, R Zhou, Y Sun… - Frontiers in cell and …, 2021 - frontiersin.org
Mitogen-activated protein kinases consist of a group of serine/threonine protein kinases, …
the proliferation of renal fibroblasts and accelerated the development of renal interstitial fibrosis …

MP16-08 TRIB3 PROMOTES THE PROLIFERATION AND INVASION OF RENAL CELL CARCINOMA CELLS VIA ACTIVATING MAPK SIGNALING PATHWAY

B Hong, K Ma, J Zhou, H Xie, K Zhang, L Li… - Journal of …, 2019 - journals.lww.com
… We here report the critical roles of a mitochondrial PRELID2 in renal carcinogenesis. … is
likely to play a crucial role in renal carcinogenesis though its interacting with mitochondrial PHB2. …

Renal ciliopathies

LA Devlin, JA Sayer - Current Opinion in Genetics & Development, 2019 - Elsevier
Mitogen-activated protein kinase-binding protein 1 Scaffold protein for mitogen-activated
protein kinases, which is key for regulating JNK and NOD2 signalling. Non-ciliary protein, but …