Mast cells and IgE in defense against lethality of venoms: Possible “benefit” of allergy

SJ Galli, M Metz, P Starkl, T Marichal, M Tsai - Allergo journal international, 2020 - Springer
… of the venoms of six different poisonous snakes [84]. … venom or Russell’s viper venom,
which “arm” mast cells with IgE antibodies that bear specificity for components of those venoms, …

Bothrops jararacussu snake venom lectin induces mast cell activation and vascular permeability enhance in an animal model

FH Kwasniewski, AM Kayano, AN Fukunaga… - Toxicon, 2022 - Elsevier
… jararacussu snake venom, on mast cells and vasopermeability were investigated in this
study. BjcuL activates mast cells and increases vasopermeability through the involvement of …

[HTML][HTML] Snake venom rhodocytin induces plasma extravasation via toxin-mediated interactions between platelets and mast cells

Y Nakamura, T Sasaki, C Mochizuki, K Ishimaru… - Scientific Reports, 2019 - nature.com
… did not directly stimulate mast cells, and mast cells did not express CLEC-… mast cell activation
by snake venom: some toxins may activate mast cells indirectly, with platelets or other cells

[HTML][HTML] Mast cells as protectors of health

A Dudeck, M Köberle, O Goldmann, N Meyer… - Journal of Allergy and …, 2019 - Elsevier
… and elimination of toxins or venoms. MCs can enhance … Uterine tissue remodeling by α-chymase
(mast cell protease [… detoxify an increasing number of venoms and endogenous toxins. …

[HTML][HTML] Mast Cell and Basophil Granule Proteases - In Vivo Targets and Function

L Hellman, S Akula, Z Fu, S Wernersson - Frontiers in Immunology, 2022 - frontiersin.org
venoms from a number of snake species, indicating that tryptase is the dominant player in the
protection against snake venom (… as a potential treatment for snake bite envenoming. A few …

[HTML][HTML] Pain and Cellular Migration Induced by Bothrops jararaca Venom in Mice Selected for an Acute Inflammatory Response: Involvement of Mast Cells

FV Kondo, WHK Cabrera, OG Ribeiro… - Frontiers in …, 2022 - frontiersin.org
… isolated from the venom of the Bothrops pirajaí snake, and observed induction of … venom
injection induces chemotaxis (37), which can be regulated by mediators released by mast cells

Mast Cells Modulate the Immune Response and Redox Status of the Gastrointestinal Tract in Induced Venom Pathogenesis

N Zerarka-Chabane, F Laraba-Djebari… - Inflammation, 2022 - Springer
… Indeed, several investigations reported that MCs express on their surface many receptors
that interact with components of venoms (bee, spider, and snake) and neuropeptide …

IgE antibodies increase honeybee venom responsiveness and detoxification efficiency of mast cells

P Starkl, N Gaudenzio, T Marichal, LL Reber… - Allergy, 2022 - Wiley Online Library
Background In contrast to their clearly defined roles in allergic diseases, the physiologic
functions of Immunoglobulin E antibodies (IgEs) and mast cells (MCs) remain enigmatic. Recent …

[HTML][HTML] Future needs in mast cell biology

G Varricchi, A de Paulis, G Marone, SJ Galli - International journal of …, 2019 - mdpi.com
… primary immune responses to the venoms of the Gila monster … recently designated
envenomation by snake bite to its list of … six different venoms from phylogenetically distinct snakes, …

Mast cells in inflammation and disease: recent progress and ongoing concerns

SJ Galli, N Gaudenzio, M Tsai - Annual review of immunology, 2020 - annualreviews.org
… in host defense, ie, promoting resistance to certain venoms, has also been supported both
by work in mast cell–engrafted WBB6F1-Kit W/Wv and C57BL/6-Kit W-sh/W-sh mice and by …