… in sepsis can control pathogen infection, excessive pyroptosis can lead to a dysregulated …
overview of the mechanisms and potential therapeutic targets underlying pyroptosis in sepsis …

… Thus, in this review, we comprehensively elaborate on the pathophysiological mechanism
and molecular signal pathways of pyroptosis and its role in the pathogenesis of autoimmune …

… of the inflammasome pathway. We discuss available pharmaceutical agents that target a
critical component of inflammasome activation, signaling leading to cellular pyroptosis, and the …

… the molecular mechanisms of NLRP3 inflammasome in pyroptosis signaling pathway, including
… Here, we focus on the molecular mechanisms of NLRP3 inflammasome in the pyroptosis …

… the mechanisms of pyroptosis and its role as a potential therapeutic target for I/R injury. …
This section discusses the role of pyroptosis in I/R injury in different organs and possible …

… how the pyroptotic signalling pathway enhances sterile inflammation in various liver
diseases, which provide potential therapeutic targets for sterile inflammatory liver diseases. …

… and pathophysiological mechanisms of the pyroptosis-related inflammasomes pathway in
the … new insights for researchers regarding the development of potential therapies for DCM. …

… suggesting that pyroptosis signaling pathways may be potential therapeutic targets in ocular
… Active caspase-1 triggers pyroptosis via the canonical pathway, whereas activated caspase-…

… the mechanism, the diverse functions in various tumors and the potential clinical value of
pyroptosis… These findings have raised awareness of tumors and identified a number of potential …

… membrane activating pyroptosis and apoptosis. We also discuss the potentiality of pyroptosis
as a therapeutic target in human diseases. Blockade of pyroptosis by compounds can treat …