The roles of DNA, RNA and histone methylation in ageing and cancer

EM Michalak, ML Burr, AJ Bannister… - Nature reviews Molecular …, 2019 - nature.com
… DNA methylation occurs predominantly at palindromic CpG dinucleotides through the addition
of a methyl group to the 5ʹ position of the cytosine pyrimidine ring, thereby generating 5-…

The interplay between DNA and histone methylation: molecular mechanisms and disease implications

Y Li, X Chen, C Lu - EMBO reports, 2021 - embopress.org
Methylation of cytosine in CpG dinucleotides and histone … genes encoding DNA‐ and
histone‐modifying enzymes are often … how DNA and histone methylation cooperate to maintain the …

DNMTs and impact of CpG content, transcription factors, consensus motifs, lncRNAs, and histone marks on DNA methylation

J Loaeza-Loaeza, AS Beltran, D Hernández-Sotelo - Genes, 2020 - mdpi.com
methylation. The association between DNA methylation and histone methylation occurs by
the … of either DNMTs with histone methylation complex or modified histone residues. The most …

Mechanisms of DNA methylation and histone modifications

S Acharjee, S Chauhan, R Pal, RS Tomar - Progress in molecular biology …, 2023 - Elsevier
… The first class of proteins is the MBD family protein, which contains a methyl CpG binding …
MBDs and UHRFs crosstalk with methylated DNA and histone modification to repress gene …

Roles and regulation of histone methylation in animal development

A Jambhekar, A Dhall, Y Shi - Nature reviews Molecular cell biology, 2019 - nature.com
Histone methylation can occur at various sites in histone proteins… It is now apparent that
histone methylation is critical for almost all … Notably, developmental histone methylation is highly …

Arabidopsis SWR1-associated protein methyl-CpG-binding domain 9 is required for histone H2A.Z deposition

ME Potok, Y Wang, L Xu, Z Zhong, W Liu… - Nature …, 2019 - nature.com
… For histone modification ChIPs, about 0.5 g of shoots were collected from 13 DAG
seedlings grown on 1% MS plates supplemented with 1% sucrose under long-day conditions. …

[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics

S Li, Y Peng, AR Panchenko - Current opinion in structural biology, 2022 - Elsevier
… around the histone octamer upon CpG methylation was due to … (b) CpG methylation could
increase DNA bending energy to … ; CpG methylation could enhance binding of DNA to histone

Histone methylation and vascular biology

X Wei, X Yi, XH Zhu, DS Jiang - Clinical Epigenetics, 2020 - Springer
… not including histone methylation in vascular biology. In this review, we primarily discuss
histone methylation in vascular development and maturity, and in vascular diseases. …

Methyl-CpG-binding domain 9 (MBD9) is required for H2A. Z incorporation into chromatin at a subset of H2A. Z-enriched regions in the Arabidopsis genome

P Sijacic, DH Holder, M Bajic, RB Deal - PLoS genetics, 2019 - journals.plos.org
… Z sites show a distinct histone modification profile, we propose that MBD9 recognizes
particular nucleosome modifications via its PHD- and Bromo-domains and thereby guides SWR1 …

Epigenetics: An overview of CpG methylation, chromatin remodeling, and regulatory/noncoding RNAs

J Clark, JE Rager - Environmental epigenetics in toxicology and public …, 2020 - Elsevier
… in complexes containing histone deacetylases, suggesting that CpG methylation and … A
second form of histone methylation occurs at arginine and describes the transfer of methyl groups …