The methyl-CpG–Binding domain 2 and 3 proteins and formation of the nucleosome remodeling and deacetylase complex
G Leighton, DC Williams Jr - Journal of molecular biology, 2020 - Elsevier
… In this review, we discuss the formation of the NuRD complex focusing on the structures
of the different components, the critical role provided by MBD2 or MBD3, how differences in …
of the different components, the critical role provided by MBD2 or MBD3, how differences in …
Stabilization of VEGF i-motif structure by CpG methylation
K Kimura, D Oshikawa, K Ikebukuro… - … and Biophysical Research …, 2022 - Elsevier
… structure is stabilized by CpG methylation. In this study, the effect of CpG methylation on the
stability of the VEGF i-motif structure … contains four cytosines on CpG sites, and three of the …
stability of the VEGF i-motif structure … contains four cytosines on CpG sites, and three of the …
Structural basis for effects of CpA modifications on C/EBPβ binding of DNA
… To understand the effects of both CpG and CpA modification on a … The protein components
of the two structures are highly … methyl specific recognition in the higher resolution structure of …
of the two structures are highly … methyl specific recognition in the higher resolution structure of …
[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics
… with methyl-binding domains that recognize methylated CpG … their influence on nucleosomal
structure and dynamics. DNA … component of base stacking, the addition of methyl groups …
structure and dynamics. DNA … component of base stacking, the addition of methyl groups …
[HTML][HTML] Densely methylated DNA traps Methyl-CpG–binding domain protein 2 but permits free diffusion by Methyl-CpG–binding domain protein 3
… In the current work, we focus on the structure and dynamics of the MBD2 and MBD3
proteins. These two highly homologous proteins arose from a duplication of the ancestral MBD …
proteins. These two highly homologous proteins arose from a duplication of the ancestral MBD …
Structural dynamics of DNA depending on methylation pattern
… A methyl group (−CH3) binds to the cytosine base in a CpG … structural variation of the DNA
model was characterized by the ratios of the square root of the three principal components of …
model was characterized by the ratios of the square root of the three principal components of …
Sequence determinants, function, and evolution of CpG islands
A Angeloni, O Bogdanovic - Biochemical Society Transactions, 2021 - portlandpress.com
… DNA methylation (5mC) and methyl-CpG binding proteins (MBDs)… provides rigidity to the
domain structure. Binding is mediated … diverse readers including components of COMPASS and …
domain structure. Binding is mediated … diverse readers including components of COMPASS and …
[HTML][HTML] Complete profiling of methyl-CpG-binding domains for combinations of cytosine modifications at CpG dinucleotides reveals differential read-out in normal and …
BC Buchmuller, B Kosel, D Summerer - Scientific Reports, 2020 - nature.com
… hMBD3, a key component of the Mi-2/… structure-function-relationships reveal markedly
different abilities of the human core family MBDs to discriminate between cognate mC/mC CpG …
different abilities of the human core family MBDs to discriminate between cognate mC/mC CpG …
How methyl–sugar interactions determine DNA structure and flexibility
K Liebl, M Zacharias - Nucleic acids research, 2019 - academic.oup.com
… allow switching on or off interactions with the methyl groups in several DNA sequences,
we … methyl groups and DNA backbone fine structure. Whereas methyl-solvent and methyl–…
we … methyl groups and DNA backbone fine structure. Whereas methyl-solvent and methyl–…
A methyl-TROSY approach for NMR studies of high-molecular-weight DNA with application to the nucleosome core particle
G Abramov, A Velyvis, E Rennella… - Proceedings of the …, 2020 - National Acad Sciences
… to study structural and motional properties of both the DNA and the protein components in
… mononucleosomes establish that CpG methylation does not perturb the structure of the NCP …
… mononucleosomes establish that CpG methylation does not perturb the structure of the NCP …
相关搜索
- methyl cpg binding domain protein
- methyl cpg nucleosome remodeling
- methyl cpg dna hyper methylation
- methyl cpg complete profiling
- methyl cpg binding analysis
- methyl cpg nervous system
- supra molecular structure methyl groups
- chromatin structure cpg methylation
- stability and structure cpg methylation
- methyl cpg histone deacetylase core
- methyl cpg dna traps
- methyl cpg nurd complex
- methyl cpg intrinsically disordered region
- methyl cpg active dna demethylation
- methyl cpg transcriptional gene
- methyl cpg cytosine modifications