… binding for methylated or unmethylated DNA, motifs with CpGs in the center were not bound
when methylated and motifs with CpGs in the flank were bound when methylated [45]. This …

… Although we currently still lack concrete evidence, it is plausible that a major function of
mammalian DNA methylation is transitioning between, rather than maintaining cellular states. …

… context of CpG dinucleotides are methylated in mammalian genomes. … methylation-sensitive
TFs, we identify and validate new factors that are blocked from binding their motifs by DNA …

… methylated or unmethylated, indicating that binding of transcription factors and DNA methylation
are … Certain transcription factors are sensitive to CpG methylation: a recent survey of 542 …

… While we provide compelling evidence that numerous TFs bind differentially to methylated
and non-methylated DNA, ChIP-BS-seq experiments (27) will be required to confirm these …

… In somatic cells, changes in DNA methylation typically reflect active transcription factor binding
to CpG-poor distal enhancers, which tend to equilibrate to intermediate levels and exhibit …

… transcription factors octamer-binding transcription factor 4 (OCT4), Krüppel-like … of DNA
transposons (UCON29) are hypomethylated, marked as enhancers by mono-methylation of …

… indicate that DNMT1 prefers DNA substrates containing hemi-methylated CpG sites [16].
Dnmt1 expression is activated by cell cycle-dependent transcription factors and thus is present …

… the gains in transcription factor occupancy in unmethylated or hyperacetylated cells were
directly associated with increased chromatin accessibility. For each transcription factor, we …

… DNA methylation at cytosine residues is one of the earliest forms of epigenetic modifications
identified in mammals and is regulated by the action of DNA methyltransferases (DNMTs) …