[HTML][HTML] Aneuploidy and DNA methylation as mirrored features of early human embryo development

EN Tolmacheva, SA Vasilyev, IN Lebedev - Genes, 2020 - mdpi.com
… undergo two waves of DNA methylation reprogramming. Failure of these … chromosome
segregation during cell division. Abnormal methylation due to errors in the reprogramming

Evaluation of genome-wide DNA methylation profile of human embryos with different developmental competences

M Yang, X Tao, K Scott, Y Zhan, RT Scott Jr… - Human …, 2021 - academic.oup.com
Reprograming of DNA methylation is highly dynamic during … of conducting methylation profile
analysis and aneuploidy screening … 3, we present the chromosomal methylation level of 4 …

[HTML][HTML] Reprogramming of DNA methylation is linked to successful human preimplantation development

J Arand, RA Reijo Pera, M Wossidlo - Histochemistry and Cell Biology, 2021 - Springer
… importance of DNA methylation reprogramming for successful … for global reprogramming of
DNA methylation and detected … suggest that DNA methylation reprogramming is conserved …

LINE-1 retrotransposon methylation in chorionic villi of first trimester miscarriages with aneuploidy

SA Vasilyev, EN Tolmacheva, OY Vasilyeva… - Journal of Assisted …, 2021 - Springer
… 13 and 18 [42] and aneuploidy of the X chromosome [44], in … one of the epigenetic genome
reprogramming waves, in … Periods of epigenetic genome reprogramming and aneuploidy

Epigenetic landscape in human aneuploid embryos

S Vasilyev, E Tolmacheva, V Demeneva… - … of Genome Regulation …, 2022 - elibrary.ru
… two waves of DNA methylation reprogramming. Abnormal … of an entire additional chromosome,
or chromosome loss, can … Therefore, in this study, a genome-wide DNA methylation

[HTML][HTML] Epigenetic Reprogramming in Mice and Humans: From Fertilization to Primordial Germ Cell Development

A Singh, DA Rappolee, DM Ruden - Cells, 2023 - mdpi.com
… After complete erasure of the DNA methylation, de novo methylation of the PGCs is where
… by mitotic chromosomal nondisjunction, resulting in aneuploidy. CPM aneuploidy can cause …

Selective targeting of TET catalytic domain promotes somatic cell reprogramming

AK Singh, B Zhao, X Liu, X Wang, H Li… - Proceedings of the …, 2020 - National Acad Sciences
… DNA methylation at the 5′-position of … Sex-chromosome dosage (SCD) effects on human
gene expression are central to the biology of sex differences and sex-chromosome aneuploidy

[HTML][HTML] New insights into X-chromosome reactivation during reprogramming to pluripotency

A Panda, JJ Zylicz, V Pasque - Cells, 2020 - mdpi.com
… of sex chromosomes and dosage compensation mechanisms. The natural aneuploidy of the
X chromosome in … In summary, it is thought that DNA methylation plays an important role for …

DNA methylation analysis and editing in single mammalian oocytes

Y Wei, J Lang, Q Zhang, CR Yang… - Proceedings of the …, 2019 - National Acad Sciences
… Sex-chromosome dosage (SCD) effects on human gene expression are central to the
biology of sex differences and sex-chromosome aneuploidy syndromes but are challenging to …

[HTML][HTML] Karyotype aberrations in action: the evolution of cancer genomes and the tumor microenvironment

NC Baudoin, M Bloomfield - Genes, 2021 - mdpi.com
… epigenetic regulation (eg, regulating DNA methylation, histone modifications, and regulatory
non… of aneuploidy in general, genetic, epigenetic, or chromosomal events that affect specific …