[HTML][HTML] Miglitol, an oral antidiabetic drug, downregulates melanogenesis in b16f10 melanoma cells through the pka, mapk, and gsk3β/β-catenin signaling pathways
HM Kim, CG Hyun - Molecules, 2022 - mdpi.com
… Most importantly, the microphthalmia-associated transcription factor (MITF) acts as a master
… the ERK signaling pathway and suppressing the p38 MAPK signaling pathway, followed by …
… the ERK signaling pathway and suppressing the p38 MAPK signaling pathway, followed by …
[HTML][HTML] Liquiritin and liquiritigenin induce melanogenesis via enhancement of p38 and PKA signaling pathways
T Uto, T Ohta, A Yamashita, S Fujii, Y Shoyama - Medicines, 2019 - mdpi.com
… is regulated by microphthalmia-associated transcription factor (… protein kinase (MAPK) family,
including p38 MAPK (p38) and … As a key transcription factor for these proteins is MITF, we …
including p38 MAPK (p38) and … As a key transcription factor for these proteins is MITF, we …
(+)-Magnolin enhances melanogenesis in melanoma cells and three-dimensional human skin equivalent; involvement of PKA and p38 MAPK signaling pathways
T Uto, NH Tung, T Ohta, Y Shoyama - Planta Medica, 2022 - thieme-connect.com
… analysis of transcriptional factors and signaling pathways … and p38 mitogen-activated protein
kinase-dependent pathways… and microphthalmia-associated transcription factor expression. …
kinase-dependent pathways… and microphthalmia-associated transcription factor expression. …
[HTML][HTML] Elucidation of melanogenesis-associated signaling pathways regulated by argan press cake in B16 melanoma cells
T Bourhim, MO Villareal, C Gadhi, H Isoda - Nutrients, 2021 - mdpi.com
… the expression of microphthalmia transcription factor (MITF) [… Interfering with p38, MAPK
expression has been reported to … of intermediate genes of the MAPK pathway were up-regulated …
expression has been reported to … of intermediate genes of the MAPK pathway were up-regulated …
Mechanisms of 4-Dimethylamino-4'-Methoxy Chalcone in Promoting Melanin Synthesis
A Tuerxuntayi, T Abulikemu… - Natural Product …, 2022 - journals.sagepub.com
… tightly regulated by a microphthalmia-associated transcription factor (MITF), an important …
the p38 MAPK pathway induces MITF expression 29,30 and promotes tyrosinase transcription.…
the p38 MAPK pathway induces MITF expression 29,30 and promotes tyrosinase transcription.…
Anti-melanogenic effects of bergamottin via mitogen-activated protein kinases and protein kinase B signaling pathways
YC Chung, YB Kim, BS Kim… - Natural Product …, 2019 - journals.sagepub.com
… of microphthalmia-associated transcription factor. The phosphorylation status of mitogen-activated
protein kinases (MAPKs) and … The phosphorylation of p38 and JNK in MAPKs induces …
protein kinases (MAPKs) and … The phosphorylation of p38 and JNK in MAPKs induces …
[HTML][HTML] MicroRNA-370-5p inhibits pigmentation and cell proliferation by downregulating mitogen-activated protein kinase kinase kinase 8 expression in sheep …
KY Ji, RJ Wen, ZZ Wang, QQ Tian, W Zhang… - Journal of Integrative …, 2023 - Elsevier
In mammals, microRNAs (miRNAs) play key roles in multiple biological processes by
regulating the expression of target genes. Studies have found that the levels of miR-370-5p …
regulating the expression of target genes. Studies have found that the levels of miR-370-5p …
… an adaptive signal to enhance pigmentation response to environmental stressors through cAMP‐PKA‐MAPK, Rab27a/RhoA, and PI3K/AKT signaling pathways
H Tang, Y Zhang, L Yang, C Hong, K Chen… - The FASEB …, 2023 - Wiley Online Library
… MAPK- d ependent Mitf expression classical pathway is also involved in melanogenesis.LP12
activated ERK1/2 and JNK but not p38 MAPK … also downregulate the transcription factor mi…
activated ERK1/2 and JNK but not p38 MAPK … also downregulate the transcription factor mi…
[HTML][HTML] Roles of inflammation factors in melanogenesis
C Fu, J Chen, J Lu, L Yi, X Tong… - Molecular …, 2020 - spandidos-publications.com
… transcription factor microphthalmia-associated transcription … suppressing the PKA or MAPK
pathway. While cytokines such … by activating the p38/MAPK and PKA pathways, and thus …
pathway. While cytokines such … by activating the p38/MAPK and PKA pathways, and thus …
[HTML][HTML] Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways
… The cyclic AMP pathway promotes melanocyte differentiation by activating CREB and the
cAMP-regulated transcription co-activators 1–3 (CRTC1–3). Differentiation is dysregulated in …
cAMP-regulated transcription co-activators 1–3 (CRTC1–3). Differentiation is dysregulated in …