Opsin 5 is a key regulator of ultraviolet radiation‐induced melanogenesis in human epidermal melanocytes

Y Lan, W Zeng, X Dong, H Lu - British Journal of Dermatology, 2021 - academic.oup.com
microphthalmia‐associated transcription factor (MITF) activation, which leads to … (MAPK)
signalling pathway or the PKC signalling pathway. , 38 That is, phosphorylation of p38 MAPK 39 …

Polygonum multiflorum Thunb. Extract Stimulates Melanogenesis by Induction of COX2 Expression through the Activation of p38 MAPK in B16F10 Mouse Melanoma …

D Kim, HJ Kim, HS Jun - Evidence‐Based Complementary and …, 2020 - Wiley Online Library
… of melanogenic genes, such as microphthalmia-associated transcription factor (MiTF),
tyrosinase-… of the p38 MAPK pathway, thereby contributing to the enhancement of melanogenesis. …

Multiple sclerosis is linked to MAPKERK overactivity in microglia

GJA Ten Bosch, J Bolk, BA 't Hart, JD Laman - Journal of Molecular …, 2021 - Springer
… a role of MAPK pathways, in particular MAPK ERK . This is … (MC1r), microphthalmia-associated
transcription factor (MITF), … activity of MAPKs, and in particular of MAPK p38 . Conversely, …

Src inhibition induces melanogenesis in human G361 cells

KE Ku, N Choi, SH Oh, WS Kim… - Molecular …, 2019 - spandidos-publications.com
… as microphthalmia-associated transcription factor (MITF), the … As Src inhibitors activate the
p38 MAPK signaling pathways … whether inhibition of these signaling pathways attenuated the …

Molecular characterization of transcription factor CREB3L2 and CREB3L3 and their role in melanogenesis in Pacific oysters (Crassostrea gigas)

K Jiang, H Yu, L Kong, S Liu, Q Li - … and Physiology Part B: Biochemistry and …, 2024 - Elsevier
… ) are important transcription factors in the cAMP-mediated melanogenesis pathway. In this
… CREB3L3 could activate the microphthalmia-associated transcription factor (MITF) promoter …

Anti-melanogenic effects of hydroxyectoine via mitf inhibition by jnk, p38, and akt pathways in b16f10 melanoma cells

YC Chung, MJ Kim, EY Kang, YB Kim… - Natural Product …, 2019 - journals.sagepub.com
Microphthalmia-associated transcription factor induces melanin production by increasing …
Recent studies linked the phosphorylation of p38 and JNK in MAPK signaling pathways to the …

Orcinol inhibits melanogenesis in B16F10 cells via the upregulation of the MAPK/ERK signaling pathway

CL Yu, H Wu, YP Chen, F Chen… - Natural Product …, 2023 - journals.sagepub.com
… -related gene and signaling pathways was analyzed by … , and microphthalmia-associated
transcription factor (MITF). … kinase (JNK) and p38 MAPK may regulate melanogenesis by …

NRASQ61K melanoma tumor formation is reduced by p38‐MAPK14 activation in zebrafish models and NRAS‐mutated human melanoma cells

I Banik, PF Cheng, CM Dooley… - Pigment cell & …, 2021 - Wiley Online Library
… mainly through the expression of the microphthalmia-associated transcription factor (MITF)
(… µM and 100 µM anisomycin and probed for MAPK pathway proteins phospho-JNK, phospho-…

… A/Cyclic adenosine monophosphate-responsive binding protein-and p38 mitogen-activated protein kinase-mediated microphthalmia− associated transcription factor …

JU Park, SY Yang, RH Guo, HX Li, YH Kim… - Frontiers in …, 2020 - frontiersin.org
… /CREB and p38-mediated signaling pathways were involved … via PKA/CREB- and p38
MAPK-mediated MITF degradation. … on melanogenesis pathways via PKA/CREB- and p38 MAPK-…

Insights into bone morphogenetic protein—(BMP-) signaling in ocular lens biology and pathology

DY Shu, FJ Lovicu - Cells, 2021 - mdpi.com
… These include the MAPKs, p38 and the extracellular signal-… unilateral or bilateral
microphthalmia with morphologically normal … of Pax6, an essential transcription factor for early eye …