Epigenetic regulation of melanogenesis

S Zhou, H Zeng, J Huang, L Lei, X Tong, S Li… - Ageing research …, 2021 - Elsevier
… (DCT) and microphthalmia-associated transcription factor (MITF), as … MITF is the most
important transcription factor in … signal pathways, including the "MAPK signaling pathway", "cAMP …

MicroRNAs-mediated regulation pathways in rheumatic diseases

S Assadiasl, M Rajabinejad, N Soleimanifar… - …, 2023 - Springer
… be downmodulated through RANKL signaling, which in turn … .1) and microphthalmia-associated
transcription factor (MITF). … transcription factors and their upstream signaling pathways. …

[HTML][HTML] Targeting oncogenic transcription factors in skin malignancies: An update on cancer stemness and therapeutic outcomes

M Steinhoff, M Alam, A Ahmad, S Uddin… - Seminars in Cancer …, 2022 - Elsevier
… Indeed, accumulating evidence indicates that deregulation of transcription factors (TFs)
due to genetic, epigenetic and signaling distortions plays essential role in the development of …

A comprehensive review on MAPK: a promising therapeutic target in cancer

C Braicu, M Buse, C Busuioc, R Drula, D Gulei… - Cancers, 2019 - mdpi.com
… to MAPK pathway inhibitors also via an increased number of tumor-associated macrophages,
and TNFα and MITF (microphthalmia transcription factor) … through ROS/p38 MAPK [148]. …

The biological relevance of pigment epithelium-derived factor on the path from aging to age-related disease

R Abooshahab, CR Dass - Mechanisms of Ageing and Development, 2021 - Elsevier
… the apoptosis-inducing pathways, including MAPK, c-Jun N-terminal kinases(JNK), and p38,
in … senescence in melanoma cells via microphthalmia‐associated transcription factor (MITF). …

Linarin enhances melanogenesis in B16F10 cells via MAPK and PI3K/AKT signaling pathways

SY Oh, JK Kang, CG Hyun - Journal of Applied Biological …, 2021 - koreascience.kr
… 1 (TRP-1), and microphthalmia-associated transcription factor (MITF) that are related to …
kinase (MAPK), phosphatidylinositol 3-kinase (PI3K), and protein kinase B signaling pathways in …

[HTML][HTML] The long noncoding RNA UCA1 negatively regulates melanogenesis in melanocytes

S Pei, J Chen, J Lu, S Hu, L Jiang, L Lei… - Journal of Investigative …, 2020 - Elsevier
… is regulated by a series of transcription factors, among which microphthalmia-associated …
in the cAMP/PKA, MAPK, Ca 2+ /CaMK, and PI3K/Akt signaling pathways. Both the expression …

[PDF][PDF] Biomedical activity of natural product related with p38 MAPK pathway

YM Kim, JH Park, YJ Lee - 2024 - hantopic.kr
… EF reduces both protein and mRNA levels of microphthalmiaassociated transcription factor.
EF downregulates intracellular cAMP. EF increases the phosphorylation of ERK and inhibits …

Anti-Melanogenic Effects of Ethanol Extracts of the Leaves and Roots of Patrinia villosa (Thunb.) Juss through Their Inhibition of CREB and Induction of ERK and …

D Jeong, SH Park, MH Kim, S Lee, YK Cho, YA Kim… - Molecules, 2020 - mdpi.com
… the mRNA of microphthalmia-associated transcription factor (MITF… MITF is regulated by MAPKs
such as ERK, JNK, and p38 [23]… of Pv-EE in the MAPKs pathway, we performed a western …

Daphnetin inhibits α-MSH-induced melanogenesis via PKA and ERK signaling pathways in B16F10 melanoma cells

G Nam, SK An, IC Park, S Bae… - Bioscience, Biotechnology …, 2022 - academic.oup.com
… expression of microphthalmia-associated transcription factor, a mastering transcription factor
of … Interestingly, Figure 5c shows that the phosphorylations of JNK and p38 MAPK were not …