… has implicated mitochondrial reactive oxygen species (mtROS) in … mitochondria-targeted
inhibition of the oxidative stress in vivo to alleviate the clinical symptoms and lung inflammation …

… Mitochondrial reactive oxygen species are mainly produced at the electron transport chain
(ETC) during the oxidative phosphorylation process, during which molecular oxygen (O 2 ) is …

… and reactive oxygen species (ROS) as the most accepted cause of aging and numerous
inflammatory diseases. … of replication errors of mitochondrial DNA (mtDNA) and toxic adducts on …

… Increasing evidence points to the respiratory Complex II (CII) as a source and modulator
of reactive oxygen species (ROS). Both functional loss of CII as well as its pharmacological …

… with complex III (CIII) (supercomplex I + III 2 ) or CIII+complex IV (CIV) (N-respirasome), a
particularly relevant feature for mitochondrial reactive oxygen species (ROS) production. …

… Our studies support the relevance of targeting the mitochondrial enzyme MAO to counteract
inflammatory diseases for several reasons. Indeed, MAO inhibitors, for which the mechanism …

… reactive oxygen species (ROS) production. This is particularly salient when considering
mitochondria… In addition to energy generation, mitochondrial metabolism predisposes cells to the …

… Mitochondria in aerobic eukaryotic cells are both the site of energy production and the
formation of harmful species, such as radicals and other reactive oxygen species, known as ROS. …

… and stimulate innate immune signaling cascades to intensify the inflammatory response at
… of mitochondrial-derived reactive oxygen species (ROS) contribute to mito-inflammation, a …

… of cancer, cardiovascular diseases, diabetes, neurological disorders (Alzheimer’s and
Parkinson’s diseases, Down syndrome), psychiatric diseases (depression, schizophrenia, bipolar …