… Apart from the nuclear DNA, a mammalian cell contains multiple copies of mitochondrial
DNA (mtDNA), which is a circular molecule of ~16.5 kb in humans that only encodes 13 …

… as mitochondrial DNA (mtDNA), which in mammalian cells contains 37 … mitochondria (1–3).
Besides these proteins, however, most (99%) of mitochondrial proteins in mammalian cells …

… Mammalian mitochondria contain multiple copies of a circular, double-stranded DNA … In
this review, we discuss our current understanding of mtDNA replication in mammalian cells and …

… Here we describe first-in-class specific inhibitors of mitochondrial transcription (IMTs) that
target the human mitochondrial RNA polymerase (POLRMT), which is essential for biogenesis …

… In the present study, we successfully generated mammalian cells stably transduced with
mitochondrial Stat3 and analyzed the contribution of mitoSTAT3 in the cell response against …

… the mammalian cells (21). Additionally, an in vivo murine model of mtIF3 deficiency has
revealed that mtIF3 is indispensable for mitochondrial … shut down mitochondrial translation (22). …

… roles, mitochondria as signaling organelles dictate stem cell fate … ideas on how mitochondria
control mammalian stem cell fate and … , pyruvate metabolism, and mitochondrial dynamics. …

… encoding mitochondrial proteins that increase respiratory activity. We find that in both yeast
and mammalian cells, Ire1 and calcineurin each contribute to the mitochondrial response to …

… Here, we provide a detailed ribosome profiling protocol optimized to interrogate mitochondrial
translation in mammalian cells (MitoRiboSeq), wherein mitoribosome footprints are …

… mitochondrial respiration to facilitate cellular adaptation to different metabolic and growth
conditions. In particular, we focus on transcriptional, … that promote mitochondrial respiratory …